40 mgs oxandrolone is way too much - be sure 911 is in your cell as you'll need to call it when you have massive cardiac arrest - - oxandrolone throws yours lipid profile (cholesterol) way way off - - you will be unable to control your HDL from plummeting - the other you can control, maybe, with lots of lipid lowering sups - like red yeast rice, metamucil, etc. Be CERTAIN to take a blood test BEFORE you start and then mid cycle so you can see your lipid profile be completely fucked - - yea OX rocks - killer pumps, strength, hard look, put on 7-8 lbs of ripped muscle -but I've done it a few times and guarantee the calcification in your arteries will increase significantly