My PGF2a is due any day now and I plan to put my whole experience in this thread, here is a little more info I have collected on PGF from Meso-RX
The beginner schedule
Inject PGF2 (half a ml.) 30 minutes after the noon lunch. Inject the whole half a ml. at only one place. Your lunch should be high in proteins and carbs while low in fats. Make sure you have a serving of weight gainers at hand during the next two hours. This has two purposes. First, some people report a hypoglycemia-like feeling after PGF2. Of course this side effect should be countered. Eating a liquid meal generally makes them feel better. Second, whenever anabolism is elevated, so should be protein feeding frequency. Repeat a similar procedure after the evening meal. Change the side of injection.
For the most daring, adding an insulin booster before the meals may be a good idea. I like Glipizide (2.5 mg) but Glibenclamide (the insulin booster of reference) has been shown to lessen the incidence of side effects of PGF2 especially on the intestine. For Glibenclamide, start with the 1.25 mg pills and build up to the 2.5 mg. This makes it a smart stack to enhance anabolism while reducing side effects. Of course, you should be extra careful about the potential hypoglycemia so make sure you ingest some carbs every 30 minutes for the next two hours when it is time for the weight gainers. I suggest that you increase your creatine intake according to your PGF2 dosage as prostaglandins like most other anabolic substances accelerate the wasting of creatine. Go with at least 10 grams of creatine per day.
The advanced schedule
This is not a pro schedule. It should rather fit most of the readers' needs for muscles. As you taper off your steroid intake, slowly build up your PGF2 intake first in terms of dosage, then in terms of frequency. The animal studies suggest that PGF2 tends to depress testosterone secretion. But the PGF2 users usually get very "horny", which is a good sign, especially at the end of a steroid cycle. And do not discount the general hardening properties of PGF2 which amazingly is not restricted to skeletal muscles.
Frequency of administration as well as dosage should be increased compared to beginners. You also have the choice between insulin injections and oral insulin boosters. Sticking with the oral booster may be wiser until you get more comfortable with the control of your glycemia. This is especially true as PGF2 will enhance the hypoglycemic effects of insulin. Wake up and have a liquid meal followed by a more solid meal within 30 minutes. Use that period for an insulin shot (start low with 5 UI and build up to no more than 15 UI per meal) or for oral Glipizide (2.5 to 5 mg). Prefer a long acting insulin to a short one. Wait for 15 minutes before your PGF2 (always start low and build up as you feel more comfortable). Repeat this procedure at lunch. Keep the liquid meal for after the lunch in case you feel hypoglycemia. Another reason to prefer Glipizide at that time is that you may get tired of the frequent injections.
Repeat this procedure after training. You can use another PGF2 injection a bit before bedtime still with a meal but without the insulin or the booster. Some people who bad-mouth the prostaglandins argue that prostaglandins depress GH secretion. This is funny as the scientific literature points out the opposite. GH should be liberated overnight.
As you use more PGF2 than in the beginner cycle, go with at least 15 grams of creatine over 24 hours.
The science of cycling
The length of a PGF2 cycle is generally determined by default. The cycle usually lasts the whole time you want to be off steroids. It means it can go from between 24 hours to two months. Even though bodybuilders welcome a drug that allows them to grow while off steroids, most will get tired of using PGF2 after a while. They are usually happy to switch back to anabolics. A good rule of thumb is therefore to use PGF2 until you get tired of it. Again, there is no magic number here.
Yet many maintain a lighter intake of PGF2 centered around their weak bodypart. A lighter schedule includes one or two injections a day in a weak bodypart such as the calves to help bring them up but without having to go with all the trouble associated with normal PGF2 use.
To conclude, I again would like to quote Dan Duchaine about steroids in USH II:
"Rule #7: Most people who have taken massive amounts of steroids don't get sick, don't die, and don't go crazy.
Rule #8: ... Never assume that you are like 'most people' until you prove it."
This exact same rule apply to PGF2 users. Do not assume that PGF2 use is benign. PGF2 will affect every one of the cells composing your body. You are not immune from a rare, unexpected reaction. Please do not consider PGF2 usage lightly. We would not like to hear from you in the horror story section of a bodybuilding magazine.
I looked into running slin with my pgf2a but it was way too complicated. between the frequent shots and avoiding going hypo from the insulin I would basically be busy 24/7 plus my 6 meals a day would have to be altered so i said fuck it
I am however very curious about avoiding the shits! Here is something unpleasant to think about but maybe useful. You know when you swallow a piece of gum how it toughens up your shit? like if you swallow 4-5 pieces in a day it will make you almost constipated! Can someone explain to me why this is? ( I am guessing because of the trouble of digesting the thick gum). If I can avoid the shit by swallowing a piece of gum before each shot I am in!
ANd if this idea is totally dumb, atleast I am thinking people!
Anyone else tried pgf2a since this thread was last updated?