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nolvadex to prevent d-bol bloat?

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Everytime i've added Nolva to a cycle I notice my veins out and a more hard look usually within a week so I believe it does keep the water bloating down.
 
jc21 said:
well i dont think nolva will cut down on the bloat from the estrogen. because nolva just stops the estrogen from bonding to certain places. i think you will need armidex/liquidex to stop the overall aromitization.

"stops the estrogen from bonding to certain places"....???

how does water retension occur? steroid aromatises to estradiol, estradiol binds (does not bond) to its receptor site and initiates a signal, then aldosterone upregulates causing sodium retension. if estradiol is does not bind, aldosterone is unchanged so no sodium retension occurs (no water bloat), aromatise inhibitors (arimidex, femera, aromasin) bind to enzyme aromatise changing its structure therefore deactivating it completely, in the end both processes work, degree to which they both work will vary from individual to another, some will have less water with arimidex some will have less water with nolvadex (in extreme cases some might be so sensetive to estrogen that nolvadex will agravete their breast tissue), botom line: GENETICS
 
the issue of Nolva effectivness with respect to water retention is the fact that it is a SERM.. thus depending on the tissue it will either act as an antagonist or agonist.. in breast tissue it is antagonist and it has high binding affinity (this varies from tissue to tissue)..
 
F you guys and your 3 dollar arimidex!!! hehe. take care fellas.
 
grrrr. College towns suck. No local source. Mail order this, mail order that. I just wanna get big!! (sobbing)
 
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