Nolva vs. Arimedex!

[the sledgehammer]

Since Adex is expensive as hell, Can one substitute nolva for it @ 20mg/ day instead of the recommended dose of 1mg/day of Arimedex? Adex is the best for a reason, but the funds are low at the moment yet i still want to do my cycle right.

 

[adam wj]

http://www.ibelabs.net/aqs.htm

i know you can afford that

 

[the sledgehammer]

I know, but I heard they were having trouble shipping. I imagine they have trouble keeping up with demand with their low prices. Thanks for the idea.

 

[adam wj]

that thread on the aas board?

they were out of novladex
they have plenty of adex

good luck either way b0r, what are you gonna be taking?
you know novla wont help with bloat right?

 

[gregory]

1mg adex per day? That's hella high. .5mg EOD is more like it.

 

[Jarbeebus]

so adex is better period? and negates the need for nolva? I know they work differently, but doesn't nolva negate the effectiveness of adex?

 

[gregory]

Arimides is an aromatose inhibitor. Noladex does not stop the aromatose enzyme but blocks it's effects once they took place. In other words Nolvadex stops estrogen from connecting with a receptor site, by occupying it, it does this by looking like an estrogen itself but actually being an estrogen. So once the receptor is occupied it's occupied. Arimidex works on the step where it prevents you from aromatizing test into estrogen in the first place. So they don't negate each other they can actually work together quite well. Arimidex will stop all the estrogen from "happening" and anything it misses will be blocked by the nolvadex. I hope this somewhat simple explanation does it.

PS.

It's not a good idea to get rid of all the estrogen in your body. It's there for a reason. Recently there's growing evidence on how important it may be to include small ammounts of test with womens HRT. The opposite is said for men as well, small ammounts of estro are very beneficial to us as well.

 

[Jenetic]

1mg adex per day? That's hella high. .5mg EOD is more like it.

Not really. On average, arimidex suppresses estrogen by 36-59% in men. This based upon normal healthy men and does not account for the increased aromatase activity when using aromatizing AAS.

Jenetic

 

[gregory]

Not really. On average, arimidex suppresses estrogen by 36-59% in men. This based upon normal healthy men and does not account for the increased aromatase activity when using aromatizing AAS.

Jenetic

True but it depends on how "heavy" usage is. Generally speaking i feel that .5 is enought as i am not a fan of eliminating my estrogen totally. I did that with one test cycle and it sucked. The gains were dramatically reduced, i got achy joints and my cholesterol went above 220 total. Don't get me wrong i think adex has a place in every cycle, but i think too much of a good thing is well, a bad thing.

 

[Jenetic]

True but it depends on how "heavy" usage is. Generally speaking i feel that .5 is enought as i am not a fan of eliminating my estrogen totally. I did that with one test cycle and it sucked. The gains were dramatically reduced, i got achy joints and my cholesterol went above 220 total. Don't get me wrong i think adex has a place in every cycle, but i think too much of a good thing is well, a bad thing.

It's virtually impossible to hit undectable levels of estrogen.

The majority of estrogen in males is derived from the extraglandular aromatization of testosterone and androstenedione to estradiol and estrone, respectively. The testes secrete 6-10 mg of estradiol and 2.5 mg of estrone per day (15% of estradiol and 5% of estrone). This means that there are still approximately 20% Estrogens detectable, even if armoatase activity was completely stopped.

The optimal dosage will vary depending on the individual and their goal. Another alternative, for those whom are concerned, is to use 0.5 mgs arimidex ED/EOD in combination with 10 mgs nolvadex ED. This combination prevents a drastic overall reduction in estrogen (less of an impact on cholesterol) and receptor specific protection. Also, nolvadex will have an added bennefit in this equation for it's ability to increase HDL. Regardless, the elevated HDl concetrations are not permamnent and subside shortly post cycle. Cholesterol is another issue that should be controlled during cycle as well as recovered post cycle.

Jenetic