Jenetic said:It's virtually impossible to hit undectable levels of estrogen.
The majority of estrogen in males is derived from the extraglandular aromatization of testosterone and androstenedione to estradiol and estrone, respectively. The testes secrete 6-10 mg of estradiol and 2.5 mg of estrone per day (15% of estradiol and 5% of estrone). This means that there are still approximately 20% Estrogens detectable, even if armoatase activity was completely stopped.
The optimal dosage will vary depending on the individual and their goal. Another alternative, for those whom are concerned, is to use 0.5 mgs arimidex ED/EOD in combination with 10 mgs nolvadex ED. This combination prevents a drastic overall reduction in estrogen (less of an impact on cholesterol) and receptor specific protection. Also, nolvadex will have an added bennefit in this equation for it's ability to increase HDL. Regardless, the elevated HDl concetrations are not permamnent and subside shortly post cycle. Cholesterol is another issue that should be controlled during cycle as well as recovered post cycle.
Jenetic
Help me understand. As i know now, the majority of estrogen is extraglandulary produced via the aromtose enzyme. I am under the impression that fat cells complete a large portion of this process, and if so then i feel that blocking estrogen with smaller doses of arimidex and nolva (which is what i do btw)is more imprtant in a person with more fat on their frame especially if fat loss is important. Would you agree?