Nizoral, Propecia, Monoxidil etc........................

[Lenas25]

spiro (or spironolactone), propecia, finasteride, minoxidil, folligen

Can anyone help me with these drugs, has anyone used them, how at what dosage?

I just came off my fist cycle, i used D-bol, Omnadren250 and Primo for the last few weeks, while on juice i didnt have any hair loss and im not predisposed of it (i think) cause nobody in my family, all the way untill my great-grandfather who died 5 years ago. Nobody is bold on any side of my family.

Now that im 2 weeks off the juice i broke out BADLY in zits and pimples, none on face but back and arms are gone like pepperoni pizza. I starten noticing hair in the tub after every shower, and only from the front, CAN I STOP THIS? I dont want to lose my hair as its my best feature and I'm only 24 years old. How (if i can) can i regrow it or stop it dead in its tracks? Please help me out!!!!!!!!!!!

 

[Bad Black]

spiro is a topical anti-androgen that should go to work immediately. i'd jump on that. minoxidil is basically for the "bald-spot" area......proscar/finesteride takes one month or so to build itself up to usefulness, then it should start to help via stopping the aromatization to DHT. Nizoral 2% shampoo should go to work within a week or two also with daily usage. use that every day. so basically i'd go with spiro and nizoral if i were you. next time load up on proscar before you cycle with test and use it during and after as well.

 

[Lxxy]

Nizoral 2% shampoo should go to work within a week or two also with daily usage <<< no, use Nizoral 2% max 3 times per week!
In some cases Nizoral 2% cause more shedding so try first the 1%
at other times use H&s, or t-gel...
spiro 2% lotion use two times per day
or spiro 5% cream once a daY
proscar/finesteride takes one month or so to build itself up to usefulness <<< no it takes up to 6 months

hm so whats the best to do:

finesteride 1 mg daily
minoxidil 5% at the morning <<< it makes the hair looks better and stronger and it will regrowh some of them
spiro 5% cream <<< before bedtime
Nizoral 1% 2 times a week
at other days t-gel

thats best u can do but u must not take all of them!

 

[Bad Black]

Nizoral 2% shampoo should go to work within a week or two also with daily usage <<< no, use Nizoral 2% max 3 times per week!
In some cases Nizoral 2% cause more shedding so try first the 1%
at other times use H&s, or t-gel...
spiro 2% lotion use two times per day
or spiro 5% cream once a daY
proscar/finesteride takes one month or so to build itself up to usefulness <<< no it takes up to 6 months

hm so whats the best to do:

finesteride 1 mg daily
minoxidil 5% at the morning <<< it makes the hair looks better and stronger and it will regrowh some of them
spiro 5% cream <<< before bedtime
Nizoral 1% 2 times a week
at other days t-gel

thats best u can do but u must not take all of them!

totally disagree. I, and others, use nizoral 2% every day and it works great. as for proscar 1-2 months is plenty of time for it to begin to work.....where do you find this info about 6 months? and all you did was reiterate my recommendation of spiro, that i apply once nightly before bed. as well, the hair re-growth from minoxidil is a joke. i use it for preventative. but your entitled to your opinion.

 

[Bad Black]

use nizoral 2% every day and it works great <<< why to use nizoral every day when it will stay in the scalp for 3 days(HWZ)?
as for proscar 1-2 months is plenty of time for it to begin to work << no its not men read the studies plz!
and all you did was reiterate my recommendation of spiro, that i apply once nightly before bed <<< hehe no i use it in that cycle at my own
the hair re-growth from minoxidil is a joke <<< ok that right
cya

ok your the genius for the day.

 

[Lxxy]

use nizoral 2% every day and it works great <<< why to use nizoral every day when it will stay in the scalp for 3 days(HWZ)?
as for proscar 1-2 months is plenty of time for it to begin to work << no its not men read the studies plz!
and all you did was reiterate my recommendation of spiro, that i apply once nightly before bed <<< hehe no i use it in that cycle at my own
the hair re-growth from minoxidil is a joke <<< ok that right
cya

 

[Lenas25]

ok guys, thanx for the info, i can get nizoral shampoo, but can my doc prescribe me other things, also does Propecia work, i'd like to know that and also does ROGAINE do anything for hair loss.

Also what do i use for hair re-growth, i need it soon and any help would be appreciated!!!!!

Thanx for the info guys you are the best

 

[b1ewsw32]

use nizoral 2% every day and it works great <<< why to use nizoral every day when it will stay in the scalp for 3 days(HWZ)?
as for proscar 1-2 months is plenty of time for it to begin to work << no its not men read the studies plz!
and all you did was reiterate my recommendation of spiro, that i apply once nightly before bed <<< hehe no i use it in that cycle at my own
the hair re-growth from minoxidil is a joke <<< ok that right
cya

Stays in the scalp for 3 days, huh?? I assume you're refering to the 2% shampoo(20mg/g) and not the antifungal cream indicated for tinea pedis,tinea corporis and tinea cruris or for the treatment of seborrheic dermatitis or cutaneous candidiasis. Even then the recomended dose is once daily.
Ketoconazole has a short elimination half-life of 1.8 hrs after a 2.5mg/kg dose. Oral minoxidil's half-life is 4.2hrs and 5%topical is recomended 2x daily.

As for the propecia:
PRODUCT MONOGRAPH
PROPECIA®
(finasteride)
Film-coated Tablets 1 mg
THERAPEUTIC CLASSIFICATION
Type II 5 alpha-reductase inhibitor
ACTIONS AND CLINICAL PHARMACOLOGY
PROPECIA® (finasteride) is a competitive and specific inhibitor of Type II 5 alpha-reductase, an
intracellular enzyme that converts the androgen testosterone into dihydrotestosterone (DHT). Two distinct
isozymes of 5 alpha-reductase are found in mice, rats, monkeys, and humans: Type I and II. Each of
these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I
5 alpha-reductase is predominant in the sebaceous glands of most regions of skin, including scalp, and
liver. Type I 5 alpha-reductase is responsible for approximately one-third of circulating DHT. The Type II
5 alpha-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles
as well as liver, and is responsible for two-thirds of circulating DHT.
In humans, the mechanism of action of finasteride is based on its preferential inhibition of the Type II
isozyme. Using native tissues (scalp and prostate), in vitro binding studies examining the potential of
finasteride to inhibit either isozyme revealed a 100-fold selectivity for the human Type II 5 alpha-reductase
over Type I isozyme (IC50=500 and 4.2 nM for Type I and II, respectively). For both isozymes, the inhibition
by finasteride is accompanied by reduction of the inhibitor to dihydrofinasteride and adduct formation with
NADP+. The turnover for the enzyme complex is slow (t¹
₂ approximately 30 days for the Type II enzyme
complex and 14 days for the Type I complex).
Finasteride has no affinity for the androgen receptor and has no androgenic, antiandrogenic, estrogenic,
antiestrogenic, or progestational effects. Inhibition of Type II 5 alpha-reductase blocks the peripheral
conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT
concentrations. Finasteride produces a rapid reduction in serum DHT concentration, reaching 65%
suppression within 24 hours of oral dosing with a 1 mg tablet.
In men with male pattern hair loss (androgenetic alopecia), the balding scalp contains miniaturized hair
follicles and increased amounts of DHT compared with hairy scalp. Administration of finasteride
decreases scalp and serum DHT concentrations in these men. By this mechanism, finasteride interrupts
a key factor in the development of androgenetic alopecia in those patients genetically predisposed.

The minoxidil's efficaciousness is enhanced with the synergistic combo of propecia and nizoral @2% let alone @5%.
: J Dermatol. 2002 Aug;29(8):489-98. Related Articles, Links


Comparative efficacy of various treatment regimens for androgenetic alopecia in men.

Khandpur S, Suman M, Reddy BS.

Department of Dermatology and S.T.D., Maulana Azad Meical College and Associated Lok Nayak Hospital, New Delhi, India.

Our understanding of the aetiology of androgenetic alopecia (AGA) has substantially increased in recent years. As a result, several treatment modalities have been tried with promising results especially in early stages of AGA. However, as far as has been ascertained, there is no comprehensive study comparing the efficacy of these agents alone and in combination with each other. One hundered male patients with AGA of Hamilton grades II to IV were enrolled in an open, randomized, parallel-group study, designed to evaluate and compare the efficacy of oral finasteride (1 mg per day), topical 2% minoxidil solution and topical 2% ketoconazole shampoo alone and in combination. They were randomized into four groups. Group I (30 patients) was administered oral finasteride, Group II (36 patients) was given a combination of finasteride and topical minoxidil, Group III (24 patients) applied minoxidil alone and Group IV (10 patients) was administered finasteride with topical ketoconazole. Treatment efficacy was assessed on the basis of patient and physician assessment scores and global photographic review during the study period of one year. At the end of one year, hair growth was observed in all the groups with best results recorded with a combination of finasteride and minoxidil (Group II) followed by groups IV, I and III. Subjects receiving finasteride alone or in combination with minoxidil or ketoconazole showed statistically significant improvement (p<0.05) over minoxidil only recipients. No signifcant side-effects related to the drugs were observed. In conclusion, it is inferred that the therapeutic efficacy is enhanced by combining the two drugs acting on different aetiological aspects of AGA.

 

[jacshelb]

Good info, but don't forget dutasteride. It works like propecia, but it blocks both DHT forming enzymes (hey, I'm no chemist- but this basically explains it!).

Jacob

 

[Lenas25]

thanx guys, what is the dutasteride, and how do i get it, would it be good for the cycle, and im planning next (my second) cycle at 750mgs of durates a week for 10 weeks combined with some primo at the last 4 weeks at strength of 300 mgs a week.

While im on cycle what do i take????