never use finasteride or spiro around a pregnant woman

[gonelifting]

I`ll be looking into it....but bump for more opinions.

 

[Razorguns]

This is false. If there REALLY was a danger -- the FDA would've put out an advisory or told men to use condoms. but they didn't. Bunch of 2nd rate scientists spewing out garbage.

 

[3ccEOD]

The product label states "tablets should not be handled by women due to damage to an unborn fetus"

Listen to the TV commercial real close next time it mentions it there also.
Never read or heard anything about trying to concieve while on it causing problems.

 

[b1ewsw32]

I`m planning on using Spiro and finasteride for a long time and my wife will get prego eventually. Will washing hands be enough? This is scaring me. I`d rather be bald!!!

I would definitely not use any finasteride, if you're planning a pregnancy! as systemic concentrations, through oral use has been shown to cause birth abnormalities in the male fetus.

As far as handling crushed tablets, then making contact with a female(handshake), there is little need for concern. Also spiro is not a risk factor.

This is from the Journal of American Obstetrics and Gynecology:

We read the letter by Groves and Corenblum (Groves TD, Corenblum B. Spironolactone therapy during human pregnancy. AM J OBSTET GYNECOL 1995;172:1655-6) with great interest. They successfully applied a high dose of spironolactone (200 to 400 mg/day) during pregnancy in a patient with Bartter's syndrome. Because this treatment failed to produce any antiandrogen effect in male infants and later puberty, the authors suggest that the fear of undervirilization of a male fetus may be unfounded. However, the strong natriuretic effect of spironolactone may result in a decrease of plasma volume, leading to the risk of intrauterine growth retardation. Therefore the application of high doses of spironolactone still requires caution.

The proper medication for maternal Bartter's syndrome has not yet been determined because the side effects of applied medication on the fetus are less known and maintenance of a stable, normal potassium level is difficult. Amiloride therapy was applied by Almeida and Spinnato,1 and the potassium requirements and dose of amiloride progressively increased during the second trimester.

We reported the treatment of a woman with Bartter's syndrome who had two uneventful pregnancies and was delivered of healthy male and female infants.2 In our case a combined medication of spironolactone (25 mg/day) and captopril (25 mg/day) and potassium supplementation (12 gm/day in the first pregnancy and 8 gm/day in the second pregnancy) was able to stabilize the serum potassium level throughout the pregnancies. We observed no signs of undervirilization in our male infant. Fetal diuresis and the volume of amniotic fluid, which was monitored by ultrasonographic examination, showed no pathologic alterations through the two pregnancies.

Our observation suggests that a low dose of spironolactone, combined with a low dose of captopril and potassium, may prove to be an effective and probably safe therapy in maternal Bartter's syndrome.

Keep in mind that this woman delivered a healthy male fetus,without complications, on an oral dose of 25mgs/day of spironolactone. I dont think that a male using a 2% or 5% topical solution or creme would pose any problems via transmission through body fluids(semen) or skin on skin contact.

Here's my previous post regarding crushed finasteride tabs:

http://www.elitefitness.com/forum/showthread.php?t=258799

B32

 

[b1ewsw32]

bump ^^^^^^^^^^^^^

 

[gonelifting]

bump ^^^^^^^^^^^^^

If there`s truth to this AND I`M NOT TAKING ANY CHANCES. This should be a sticky because there are A LOT of bros here taking this stuff. I`m not sure they know all these things.

Who knows I may just go the Nioxin route as others here have said it worked for them.

 

[GoldenDelicious]

the risk is overstated in this thread. sure its a category X drug and shouldnt be taken by women, but the absolutely tiny amounts that would result from normal handling, inhalation of powder, or touching someone who has handled the drug arent really significant. heck i have handled chemotherapy agents which cause cancer and the protocol is just to use gloves or tweezers and avoid inhaling the powder.

so unless your pregnant wife is snorting lines of the powder residue then you need to chiiiiiiiill

 

[AlwaysOn]

GENITALIA DEFECTS ARE WELL DOCUMENTED

come on, it makes sense too. A male fetus needs DHT to differentiate the external structures into penis and scrotum. Finasteride blocks DHT, necessary for this differentiation.

this has nothing to do with concieving. It has to do with your son's genitalia.

 

[AlwaysOn]

the risk is overstated in this thread.

go look at the primary journal articles, like I have, and then come back. Even minute amounts cause genitalia defects.

this thread should be stickied!

 

[AlwaysOn]

Contact can occur in these ways:

1. Crushed tablets. Even if you are the one handling the tablets, wear gloves.

2. Semen-yeah thats right, I'm not making this up, its in the literature.

3. Spiro cream can get on anything