yeah i'm super gyno sensitive, used to get it from just pro hormones, and got it from 500 test only so i usually take 0.125mg letro ed and that keeps the gyno at bay and doest effect my sex drive or joints at all. Used to run it at 1.25mg e3d and it was killing me so took the lowest dose i could while keeping sides away, found super small doses more frequently worked the bestt