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Insulin Resistance

Jenetic

Don Anabolico
Platinum
Insulin is a natural hormone made in the pancreas and is needed to help sugar enter your cells. Insulin is the key that opens the cell door to allow sugar inside. The sugar is used for energy after entering the cell. Insulin resistance occurs when your body does not properly use the insulin that it makes.

A basic method to test for insulin resistance at home is with a variation of the glucose tolerance test performed by doctors to determine if you are diabetic or not. The goal of this test is to see how long it takes for your pancreas to bring blood glucose levels down below the high normal range which is 105 mg/dl.

To perform this test you will need a glucometer, test strips and orange juice. Begin by establishing fasting baseline values. You will test your blood glucose after drinking a 16-24 fluid ounce glass of orange juice. This yields approximately 50-80 grams of sugar. Monitor yourself every 30 minutes for a total of 120 minutes (30 minutes, 60 minutes, 90 minutes and 120 minutes). Do not consume any additional food during this period of time.

If your blood glucose level has not gone above 105 mg/dl after 30-60 minutes, discontinue the testing as you are within normal ranges and have nothing more to discover.

60 minutes after drinking 16-24 fluid ounces of Orange juice, a key indicator of borderline insulin resistance is when blood glucose rises equal to or is >120 mg/dl, but does not exceed 180 mg/dl, then decreases itself equal to or <105 mg/dl in 120 minutes or less.

60 minutes after drinking 16-24 fluid ounces of Orange juice, a key indicator of insulin resistance is when your blood glucose level rises equal to or is >140 mg/dl and does not decrease itself equal to or <105 mg/dl for more than 120 minutes.

If your blood glucose rises equal to or is >180 mg/dl, you are more than likely diabetic.

These are basic guidelines and should not be taken as precise figures in determining diabetes. If you do happen to fall within the moderate to severe ranges, I would recommend that you consult with a physician to undergo the appropriate procedures for a proper diagnosis.

Jenetic
 
Great information.
 
in the am when i perform this test my sugar levels do not rise as much and return to normal much much faster (7-8am)

at nite it spikes fast and takes longer to return to baseline

not sure if this is standard or not
 
Very good post, Jenetic. I am no where near contemplating using insulin, however, if I choose to later down the road - I will be reviewing this thread and testing myself.

Thanks man!
 
That sound like a good home test, but who has a glucometer laying around? I know a few people with type I diabetes. I've only tested my BS once. You can just go to your doctor and get tested, right?
 
Great post. I would imagine it would be interesting to perform this home test before starting slin...and then after a cycle to determine the effects on your own personal propensity to become resistant.
 
Why is everyone saying "Oh this is a great test to know if its ok for me to start insulin". Fuck, if you have insulin resistance you need to do something about it regardless of starting insulin... for your health and your gains. Insulin resistance will reduce your gains in LBM, and make losing bodyfat more difficult.

This is why I am very much opposed to peeps using whey/dextrose shakes post workout.
 
Jenetic said:
Insulin is a natural hormone made in the pancreas and is needed to help sugar enter your cells. Insulin is the key that opens the cell door to allow sugar inside. The sugar is used for energy after entering the cell. Insulin resistance occurs when your body does not properly use the insulin that it makes.

A basic method to test for insulin resistance at home is with a variation of the glucose tolerance test performed by doctors to determine if you are diabetic or not. The goal of this test is to see how long it takes for your pancreas to bring blood glucose levels down below the high normal range which is 105 mg/dl.

To perform this test you will need a glucometer, test strips and orange juice. Begin by establishing fasting baseline values. You will test your blood glucose after drinking a 16-24 fluid ounce glass of orange juice. This yields approximately 50-80 grams of sugar. Monitor yourself every 30 minutes for a total of 120 minutes (30 minutes, 60 minutes, 90 minutes and 120 minutes). Do not consume any additional food during this period of time.

If your blood glucose level has not gone above 105 mg/dl after 30-60 minutes, discontinue the testing as you are within normal ranges and have nothing more to discover.

60 minutes after drinking 16-24 fluid ounces of Orange juice, a key indicator of borderline insulin resistance is when blood glucose rises equal to or is >120 mg/dl, but does not exceed 180 mg/dl, then decreases itself equal to or <105 mg/dl in 120 minutes or less.

60 minutes after drinking 16-24 fluid ounces of Orange juice, a key indicator of insulin resistance is when your blood glucose level rises equal to or is >140 mg/dl and does not decrease itself equal to or <105 mg/dl for more than 120 minutes.

If your blood glucose rises equal to or is >180 mg/dl, you are more than likely diabetic.

These are basic guidelines and should not be taken as precise figures in determining diabetes. If you do happen to fall within the moderate to severe ranges, I would recommend that you consult with a physician to undergo the appropriate procedures for a proper diagnosis.

Jenetic

nerd.

:heart:
 
ulter said:
Next you can explain A1C. :)

This is of course what Glucorell R addresses.

Alpha lipoic acid significantly reduces glycosylated hemoglobin (HbA1c) levels, a marker of protein glycation, sugar damaged proteins that age cells. Red blood cells contain hemoglobin, a protein that carries oxygen from the lungs to all the cells in the body. When a red blood cell first forms, it has no glucose attached to it. With diabetes, there is too much sugar in your bloodstream and that extra sugar enters the red blood cells and irreversably binds or "glycosylates" to molecules of hemoglobin. The percentage of glucose that attaches to these cells increases when blood glucose levels are elevated. HbA1c is an insightful indicator of blood glucose transport/uptake and may be used to monitor the effects of diet, exercise, and drug therapy on blood glucose in diabetic patients.

Jenetic
 
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DeltreeFitness said:
That sound like a good home test, but who has a glucometer laying around? I know a few people with type I diabetes. I've only tested my BS once. You can just go to your doctor and get tested, right?

The general idea of this thread is to give everyone some basic guidelines about insulin resistance and where they may possibly stand. Also, it may provide to be very beneficial for those whom are borderline or might already be diabetic without even knowing it. Be creative with your thinking. This test can be used in a variety of applications. For example, counteracting and monitoring the insulin resistance encountered during HGH usage.

Jenetic
 
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this test is somewhat odd, the OJ test. for at least a couple reasons.
1. highly acidic foods affect insulin response
2. OJ is, dependant on variety, going to be mostly fructose which does not require insulin for uptake.
 
macrophage69alpha said:
this test is somewhat odd, the OJ test. for at least a couple reasons.
1. highly acidic foods affect insulin response
2. OJ is, dependant on variety, going to be mostly fructose which does not require insulin for uptake.

I agree completely. However, the ammount (16-24 fluid ounces) of orange juice is enough to induce a response. We tested various times with grape juice as well. The results were similiar with grape juice being slightly more effective. If necessary, we use a dextrose solution. I'd appreciate any suggestions on how to improve things.

Jenetic
 
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cant you also use a test like this to help determine how long your "post workout window" is?

I mean after resistance training you should be more sensitive to slin then at other times of the day? or am i off with this one
 
Judo Tom said:
cant you also use a test like this to help determine how long your "post workout window" is?

I mean after resistance training you should be more sensitive to slin then at other times of the day? or am i off with this one

In general, prolonged (30-45 min) and/or high intensity exercise activity can increase insulin sensitivity and improve glucose utilization. What you can do is a comparative analysis of glucose utilization. Compare the glucose uptake of your regular meals versus your regular meals with the addition of a supplement that increases insulin sensitivity such as Glucorell R (R-ALA). You will be quite happy with what you discover.

Jenetic
 
Thanks Jenetic! K your way!!!
 
Jenetic said:
I agree completely. However, the ammount (16-24 fluid ounces) of orange juice is enough to induce a response. We tested various times with grape juice as well. The results were similiar with grape juice being slightly more effective. If necessary, we use a dextrose solution. I'd appreciate any suggestions on how to improve things.

Jenetic

a mildly flavored dextrose solution would be best (and cheaper).

grape juice has a 1:1 glucose to fructose ratio
OJ typically has a 1:2 "" """ """
 
ulter said:
But there is no variance from serving to serving.

true. However, if using as a measure of raw insulin sensitivity it is not the best choice.

if measuring changes, resulting from glucorell use, increased cardio, weight loss, etc.. it is suitable for comparative measures.
 
you never did that ulter?

honestly i didnt believe r-ala would do much for blood sugar in healthy athletes/bb but it makes a very noticeable numeric/time difference

basically my levels do not go as high and they return to baseline much much faster which leads me to believe that i get back into fatburning mode quicker as well

if you eat 4 meals with carbs a day and r-ala helps clear the sugar 30mins faster for each meal that is a lot of time you are gaining in a way.

btw ive only tested myself while cutting if that makes any difference at all.

im not exactly sure if what i think is actually working or not or how much of a difference it makes but at least i know what it is doing and it was very easy to test this as well

and regardless if it did NOTHING to my blood sugar i would take it because it is a GREAT antioxidant!!!
 
you never did that ulter?
I was referring to MP's post that the carb mix and electrolytes would make Gatorade unsuitable for an insulin resistance test. The people at Gatorade's research institute use Gatorade to do this test. I am questioning them and they should have an answer for me soon as to whether their product is unsuited for raw insulin resistance testing.

We will be testing people at stores and the plan was to tie in their product for the test. But if it's not going to give an accurate analysis we have scrub that.

It's not the test itself I posted about. :)

Thanks for posting your results.
 
This is why I am very much opposed to peeps using whey/dextrose shakes post workout



I agree with this. After cutting out the post workout shakes...and using less protein shakes in general, I've found that it's so much easier to tune body composition thru diet. Keeping insulin sensitivity high is so important.
 
Having a blood glucose meter, in general, is a very sensible idea. Monitoring blood glucose levels prior/after various types of exertio, like sprints vs low intensity cardio, heavy resistance lifting vs high volume lifting and juxtaposing the results with the effects obtained with concomitant nutraceutical administration (r-ala, alcar, green tea, bcaa, eaa, EPA/DHA, etc) is very interesting. It gives a chance to assess the efficacy and degree to which various substances modulate energy uptake and repartitioning.

Yea :nerd:
 
juve said:
Having a blood glucose meter, in general, is a very sensible idea. Monitoring blood glucose levels prior/after various types of exertio, like sprints vs low intensity cardio, heavy resistance lifting vs high volume lifting and juxtaposing the results with the effects obtained with concomitant nutraceutical administration (r-ala, alcar, green tea, bcaa, eaa, EPA/DHA, etc) is very interesting. It gives a chance to assess the efficacy and degree to which various substances modulate energy uptake and repartitioning.

Yea :nerd:

werd :o
 
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