Usually during the 5 weeks you do not have to increase. Some people tend to build up some resistance to them and will up the dose to get more results. One Russian from the board seems to not build up said resistance and continues to take them and continues to get results. If you are still getting desired rults on your dose why up it. Like I said, increase only if affects are not there for you. Myself I grow at 35mg for 5 weeks and if I stop seeing results with that dose I up it till I see more results, and continue on from there.