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How long does a bottle of dermacrine last?
- Thread starter krishna
- Start date
Derma will last you 27-30 days.
MVC10 is the $10 off coupon code.
Thanks bros.
-Pp
MVC10 is the $10 off coupon code.
Thanks bros.
-Pp
M
mikey007
Guest
You are better off buying the real deal until the jury comes back on this stuff. IMHO
needtogetaas
New member
so you get a months worth of hcg and clomid with shipping for less then 60 dolors.hmmmm well even if you do the benefits of derma are a lot more then what you get from hcg and clomid and with out all the bullshit sides you get from clomid....in fact you feel good not like a shitty bitch when you take derma dont know if many can say that about clamid!!!!!!krishna said:
krishna said:
Ya you might get it a little cheaper but I think there are plenty of other benefits to derma. Also it was not "a few testers" it was about 10. Second there are many who were skeptical and bought a bottle and now rave (Ricanx, Gjohnson to name a few), to each his own, but check out the derma threads, there are a lot of people who got nothing free offering positive anecdotes, and no negative ones that I know of.
yea, i mean PP does recommend to run HCG at the end of cycle before PCT. The clomid sides are too much, especially when the product works (dermacrine), if dermacrine worked, soso, then i would shell out money for the nolva/clomid/hcg, but since i had excelent results ill stick with it....
P.S. some of the testers did recieve free samples, but that wouldnt make us rave about a prodcut we dont believe in. The one reason for us to recieve the bottle was because we were skeptical like everyone else, and i said i would not put the banner in my sig unless i believed in the prodcut...well i added the banner after several weeks of using dermacrine....so i feel it works =]
P.S. some of the testers did recieve free samples, but that wouldnt make us rave about a prodcut we dont believe in. The one reason for us to recieve the bottle was because we were skeptical like everyone else, and i said i would not put the banner in my sig unless i believed in the prodcut...well i added the banner after several weeks of using dermacrine....so i feel it works =]
needtogetaas
New member
http://www.elitefitness.com/forum/showthread.php?t=536760
talking about clomid fucking up his eyes lol ya thats good.
again talking about clomid........
http://www.elitefitness.com/forum/showthread.php?t=522555&highlight=clomid+sides
"FUCK YOUR RIGHT THIS CLOMID SHIT SOUNDS LIKE ITS WELL WORTH THE MONEY...."
WHAT WAS i THINKING LMFAO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
solidspine said:
hipsacjack said:
http://www.elitefitness.com/forum/showthread.php?t=533110&highlight=clomid+sidestin2 said:
looks like it did not work for this guySue Me said:
Twoguns said:
DFF777 said:
jmead said:
odoyal rulez said:
bikercoz said:Just started 4th week on 50 mg liq clomid for PCT. Really no sides to speak of except the mental aspect of going from the King of the Jungle to a sniffling schoolgirl.
talking about clomid fucking up his eyes lol ya thats good.
Slyder190 said:
MR. BMJ said:
sparetire said:
again talking about clomid........
Quadsweep said:
njmuscleguy said:
trowsersnake98 said:
lifthard2005 said:
hipsacjack said:
jitc476 said:
http://www.elitefitness.com/forum/showthread.php?t=522555&highlight=clomid+sides
lesarin said:
hanibal said:
rick_hfh said:
rick_hfh said:
swede74 said:
medrep said:
get456 said:
riverrock said:
"FUCK YOUR RIGHT THIS CLOMID SHIT SOUNDS LIKE ITS WELL WORTH THE MONEY...."
WHAT WAS i THINKING LMFAO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
needtogetaas
New member
and thats just a small small tip of the ice burg i found that in 5 mins just doing a search on the word clomid.lol
Vascular Freak
New member
krishna said:
Krish....I tested it and to be honest with ya bro I wouldn't say it was good just because Pp gave me a free sample. It does seem pricey but I did feel much better post cycle. The usual post cycle sides like lack of pump, loss of strength, decreased muscle fullness etc were not noticed with this.
Mine lasted about 35-40 days. I would still run the HCG for the last few weeks of your cycle at 500 ius ed, then drop the gear and start the derma.
I don't know the test results yet but I am more concerned with sex drive, strength and muscle fullness post cycle.....all this was not an issue this time round.....I'm a straight shooter....I wouldn't kiss Pp's ass just because he let me try a bottle for free
gjohnson5
New member
I*edit*
I don't understand this be cheap stuff. You spend a ton of cash on steroids and then talk about being frugal during PCT. I would think a man who is truely frugal wouldn't do gear in the first place
*edit*
Anyway, I agree with vascular freak. When on PCT it is good to have something with anabolic properties so you can keep your gains. Clomid, Nolvadex, and HCG wont stop you from losing muscle
I don't understand this be cheap stuff. You spend a ton of cash on steroids and then talk about being frugal during PCT. I would think a man who is truely frugal wouldn't do gear in the first place
*edit*
Anyway, I agree with vascular freak. When on PCT it is good to have something with anabolic properties so you can keep your gains. Clomid, Nolvadex, and HCG wont stop you from losing muscle
krishna
New member
gjohnson5 said:
All I'm saying is why spend more when I can get proven pharmaceuticals for less? Dermacrine is a combo of AI's right? That and dhea. What is it about dermacrine that helps you keep your pumps. Maybe I'll just buy some DHEA or something post cycle. It would still be cheaper with the rest of my pct.
mobro
New member
Vascular Freak said:
So what happens when you come off of the Derma? I would start another cycle if able but what if? If the Derma raises your test what keeps the boys producing for real recovery over the long term? True we shouldn't be cheap on this but it's new and I am a skeptic. Let's hear it, and keep it simple for me(not the brightest bulb in the house)
needtogetaas
New member
Dermacrine is positively correlated to increase lean body mass and reduce fat mass through four main mechanisms: Combating cortisol dominance, increasing GH & IGF-1, increasing androgens, reducing estrogen, and increasing thermogenesis.mobro said:
Cortisol dominance can be described as having an unbalanced hormonal profile favoring cortisol activity either by having high cortisol levels, low androgen levels, or both. This hormonal shift towards cortisol dominance can be caused by excessive physical or mental stress [↑cortisol], post steroid use [↓androgen], alcohol consumption [↓androgen↑cortisol] and old age [↓androgen↑cortisol]1-4 In all cases, cortisol dominance is a condition associated with decreased muscle mass, increased fat mass, and degradation of general well being.4, 5, 17, 18, 19 Excessive cortisol activity can also decrease production of steroid hormones and androgens creating further cortisol dominance.6In order to neutralize the negative effects of cortisol and avoid cortisol dominance, one must maintain optimum levels of critical androgens.24 [Illustrated on the “Hormones” page]
DHEA is an immediate precursor to the critical androgens known as androstenediol and androstenetriol.20,21 These metabolites of DHEA are known to have powerful anti-catabolic and anti-cortisol activity by counteracting the muscle wasting and immuno-suppressive effects of cortisol.23,24 Both androstenediol and androstenetriol act as anabolic hormones and have been shown to enhance recovery and tissue repair from injury.24,25 Furthermore, DHEA, androstenediol and androstenetriol have been found to be potent enhancers of the immune system, by helping to fight off infection, protect against lethal radiation, and restore immunity during times of stress.26-29
Studies using DHEA with elderly subjects and HIV patients have also shown restoration of immune system activity by increasing the division of immune promoting cells.30-32 Its been proposed that this increased division of immunogenic cells is a result of DHEA increasing the bioavailability of IGF-1 and enhancing cellular mitosis.31
DHEA’s stimulation of IGF-1 activity is supported by other human trials.33,34 These studies have also revealed that DHEA can stimulate GH release. Therefore, the increase in IGF-1 can be explained by the increase in GH, since GH is converted to IGF-1 in the liver. An explanation for the GH release can be explained here by Suarez et al. 2005,
“it can be inferred that DHEA may release GH in vivo by reducing somatotrope responsiveness to somatostatin, as well as by enhancing somatotrope sensitivity to GHRH.”
In general terms, DHEA sensitizes the pituitary to GHRH and boosts the release of GH.34
The increase in GH and IGF-1 with DHEA supplementation has shown to have real world benefits in muscle growth, fat loss and muscle strength in various human studies.35-37 Besides having a direct effect on body composition, IGF-1 plays an important role in steroidogenic hormone production. Most notably, IGF-1 stimulates the conversion of cholesterol to pregnenolone, otherwise known as the rate limiting step in steroid hormone synthesis. Enhancement of steroidal synthesis by IGF-1 is accomplished by IGF-1’s action upon the leydig cell and stimulation of CYP11A, 3b HSD, and StAR. 38-40 Direct stimulation upon the leydig cell from IGF-1 helps initiate the first steps in creating anabolic hormones such as androstenedione, androstenediol, and t estosterone.
Concerning the process of steroidogenesis, it is known by most steroid users that anabolic androgenic steroids (AAS) inhibit natural testosterone production. However, most do not realize that AAS also inhibit DHEA production along with all other beneficial androgens.9-12 Most assume that simply using an “anti-estrogen” and inhibiting estrogen will prevent testicular shutdown and restore testosterone production, however this is not the case for the heavy steroid users. High levels of testosterone (AAS) can actually inhibit and degrade the enzymes responsible for its own creation, such as the 17a-hydroxylase enzyme.13 It can be theorized then, that all testosterone derivatives and AAS's such as stanozolol, methandrostenolone, nandrolone and even oxandrolone can directly inhibit the enzymes responsible for steroid production and cause long term suppression of steroidogenesis, aside from causing direct hypothalamus and pituitary suppression via the androgen receptor.
On the contrary, DHEA and pregnenolone appear to encourage there own production by stimulating the enzymes and hypothalamus to increase androgen production. Pregnenolone has been found to increase the release of gonadotropin releasing hormone (GnRH) from the pituitary, and thereby increase luteinizing hormone (LH) and follicle stimulating hormone (FSH) release.7 DHEA has been shown to stimulate StAR at a cellular level, therefore enhancing uptake of cholesterol into the mitochondria and up-regulating the rate limiting step in hormone synthesis.8 These properties of DHEA and pregnenolone seem to make them an excellent choice for post cycle therapy (PCT) or hypogonadal men, but there remains a problem.
Plain ol DHEA and pregnenolone are limited in there supplemental usefulness due to there eventual conversion to estrogen through interaction with the aromatase enzyme (CYP 19). Excessive estrogen can inhibit the hypothalamus pituitary testicular axis (HTPA), and increase fat deposits and water retention41. Fortunately, Dermacrine limits estrogen synthesis by including the Phyto Aromatase Inhibitor complex, consisting of three potent plant based aromatase inhibitors, namely 7,8 benzoflavone, chrysin and resveratrol.42,43 These flavonoids directly compete with aromatizing androgens for interaction with the aromatase enzyme as well and inhibit the production of the aromatase enzyme itself.44,45 As a result, estrogen is kept down, and the steroidogenic enzymes are kept up, therefore making Dermcrine one powerful hormone rejuvenator.
As another benefit to controlling estrogen levels, fat burning is made much easier. The fat loss is further catalyzed by the ingredients DHEA and 7-keto DHEA. Both of these thermogenic hormones increase calorie burning and fat loss by directly activating the mitochondrial and cytosolic thermogenic enzymes in liver.46,47.
Numerous studies with animals and humans have shown dramatic increases in fat and weight loss with the use of DHEA and 7-keto DHEA.48-51 Since DHEA is not a stimulant, the fat loss is accomplished without the jitters, anxiety or heart palpitations associated with drugs like caffeine and ephedra.
In summery, Dermacrine may help improve body composition by antagonizing cortisol, stimulating GH & IGF-1 release, raising anabolic/androgenic hormones, reducing estrogens and eliciting a thermogenic response from liver enzymes.
Dermacrine is positively correlated to support libido, erectile function and fertility through three main mechanisms: Increasing androgens, reducing estrogens and promoting healthy blood flow.
As its been discussed before, low levels of DHEA can be caused by steroid use, alcohol abuse, poor diet, lack of sleep, old age and excessive physical or mental stress. Its well established that low levels of DHEA (and testosterone) is associated with reduced sexual interest and ability.60,61 Therefore, it can be inferred that supplementing with DHEA can help support sexual function. Other androgens such as androstenedione, testosterone and their 5a-reduced metabolites; androstanedione, dihydrotestosterone, and androsterone share a strong influence on sexual function. All of these androgens have important neurobiological effects and act directly on the central nervous system to initiate sexual interest and stimulus.52 Dermacrine can incre ase these critical androgens by providing the main precursor, DHEA.
Another mechanism by which Dermacrine increases androgen production is by reducing estrogens and preventing negative feedback upon the hypothalamus pituitary testicular axis (HPTA). Our proprietary Phyto Aromatase Inhibitor complex (Phyto AI) effectively inhibits the aromatase enzyme (CYP 19) and reduces estrogen.42-45 In fact, chrysin, 7,8 benzoflavone, and resveratrol have been successfully used in animal studies to increase sperm count and fertility by inhibiting estrogen, and increasing testosterone.53,54 These animal studies also noted an “aphrodisiac” like property from these flavones, which makes sense since chrysin and 7,8 benzoflavone are the main active constituents from passion flower (passiflora incarnate) which has long been known to posses aphrodisiac like properties and has been prescribed for sexual disorders in other countries.15,16
Most importantly, the above animal studies also noted increases in both LH & FSH. As you may be aware, LH is a hormone sent from the pituitary which stimulates the testis to produce androgens, such as testosterone. Less known by most, is the importance of FSH. Without adequate FSH, LH would quickly desensitize the testis and androgen production would come to a halt, since FSH sensitizes the testis to the effects of LH by increasing the number of LH receptors in the testis. Many steroid users and/or hypogonadal men will attempt to restore their testosterone production by administering hCG (LH mimicker). However, HCG can quickly desensitize the testis and lead to further suppression of testosterone production. A better protocol would be to administer hCG with FSH (if one could obtain it), or simply buy our product.
As a final benefit, the ingredients in Phyto AI have shown to be “vasorelaxants”, which may help promote blood flow to genitalia and support erectile function.55-57
Note: Several steroidal aromatase inhibitors such as formestane (4-OHA), 1,4,6-androstatriene-3,17-dione (ATD) and androstenetrione (6-OXO) can directly inhibit the HPTA by interacting with the androgen receptor leading to a sequential reduction in LH.58,59 We DO NOT recommend the use of these steroidal based aromatase inhibitors’s.
mobro said:
It's a good question mobro. One point I would make first is that there aren't any PCT regimens that create a completely smooth transition from PCT back to natural. Anything that increases testosterone is going to have a negative feedback loop (2steps forward 1 step back). The difference between Dermacrine and other products is the self proliferation of the DHEA. In english, Your body responds to high DHEA by producing more DHEA, unlike most other hormones where the body will limit production when levels are high. This coupled with the mild AI's in dermacrine that control estrogen during a time when the body is especially susceptible to estrogen dominance as natural test is in the shitter. These plant based AI's in Dermacrine are generally more mild making them ideal for PCT as well as not being toxic, so no liver damage here either.
The bottom line is there is no "perfect PCT", you just put massive amounts of synthetic testosterone into your body and now it is hurting, the best you can do is the best you can do and dermacrine seems like a good choice.
gjohnson5
New member
I've tried dhea a number of times myself, but I agree with George that dhea is not as useful in tablet form as it is a transdermal. But to be honest the dhea / pregnenolone which caused me severe acne were sublingual tablets from ortho molecular (which I should buy some more)
I'm going to buy a lab work from Quest Diagnostics (if possible) for test , e2 estrodoil , cortisol and may LH and FSH in 2 weeks as I'm off dermacrine now. Run dermacrine for a few weeks and then buy another.
I know medical has the test kits , I just trust the real lab folks for handling samples and what not. We'll have real tests In a few weeks as I'm only running dermacrine in 2 week cycles
I'm going to buy a lab work from Quest Diagnostics (if possible) for test , e2 estrodoil , cortisol and may LH and FSH in 2 weeks as I'm off dermacrine now. Run dermacrine for a few weeks and then buy another.
I know medical has the test kits , I just trust the real lab folks for handling samples and what not. We'll have real tests In a few weeks as I'm only running dermacrine in 2 week cycles
krishna said:
needtogetaas
New member
shit sounds like a good plain bro.gjohnson5 said:
Vascular Freak
New member
krishna said:
I don't know the specifics on it....I'll plead the 5th and just say that it worked for me....better than clomid etc
Big Rick Rock
istrator
krishna,
Bro, you asked a question and got many answers. Just keep doing what you are doing if it works for ya.
-BRR
Bro, you asked a question and got many answers. Just keep doing what you are doing if it works for ya.
-BRR
T
the_clockwork
Guest
derma is legal. I'd use it
Bruce
New member
it doesn't matter derma hasnt been used for over 30 years for pct. people have been using clomid for a long time, and hcg for a while as well. aside from that they are medical drugs not something that is otc. though they are illegal for us to purchase, clomid, nolva, hcg are all fda approved. i highly doubt derma is. i just won't switch over to something because i see a few lab results. i need to see pics from solid bros who put on quality mass and used derma pct. and you can get about 2 pct's worth of clomid and hcg for 60 bucks anyday. i like how i feel on clomid, and i love blowing monster loads. i'm not knocking it but its just not realistic to start eliminating the proven pct methods because of a few people have raved. lost of free stuff if given out so people will hype shit. i'll wait a long while before i ever touch it. i just go with what works and standard aggresive pct works great for me with the cycles i useneedtogetas said:
