There is such a thing as taking too much B12. I saved a post on the subject but forgot to keep the original poster, but here it is:
The question of dose is a little subjective, but there is some benefit that has been shown from using B12 injection @ higher volume – from 1000mcg once a week to every couple days.
__
A accepted regimen for treating vitamin B12 deficiency is to initially administer 1000 mcg of the vitamin IM weekly. Lapp and Cheney treated more than 2,000 patients in a clinical setting, Initially, administering relatively small amounts of vitamin B12, but the results were inconsistent, so the dosage was increased to 2,500-5,000 mcg cyanocobalamin (subcutaneous or IM) every two to three days. Fifty to eighty percent eventually responded with an increase in energy, stamina, or well- being, usually within two to three weeks of treatment.
9. Lapp CW, Cheney PR. The rationale for using high-dose cobalamin (Vitamin B12). The CFIDS Chronicle Physicians' Forum Fall 1993;19-20.
10. Carmel R. Approach to a low vitamin B12 level. JAMA 1994;272:1233.
A double-blind crossover study, concerned men and women who complained of chronic tiredness but had no physical findings and normal serum B12 concentrations. They received intramuscular injections of 5,000 mcg of vitamin B12 or placebo twice daily for two weeks, each in random order with a two-week rest period in between. The vitamin injections resulted in a significant increase in feelings of well-being. The placebo injections had no effect, so long as placebo was given first.
14. Ellis FR, Nasser S. A pilot study of vitamin B12 in the treatment of tiredness. Br J Nutr 1973;30:277-283.
An informal study found a substantial proportion of patients with normal serum B12 concentrations felt better following injections of hydroxocobalamin but not following injections of sterile water. The maximum feeling of well-being, which was established through open trials, occurred using dosages ranging from 3000 mcg four times weekly to 9000 mcg daily.
15. Newbold HL. Vitamin B-12: placebo or neglected therapeutic tool? Med Hypotheses 1989;28:155-164.
At high doses the vitamin appears to exert a pharmacologic effect. As a drug, vitamin B12 seems to have substantial analgesic properties. Shown in open trials, patients with vertebral pain syndromes, degenerative neuropathies, and cancer noted excellent pain relief with injections of 5,000 to 10,000 mcg daily.
16. Hieber H. Treatment of vertebragenous pain and sensitivity disorders using high doses of hydroxocobalamin. Med Monatsschr 1974;28:545-548. [Article in German]
17. Dettori AG, Ponari O. Antalgic effect of cobamamide in the course of peripheral neuropathies of different etiopathogenesis. Minerva Med 1973;64:1077-1082. [Article in Italian]
You can decide for yourself how much and how often - I have done b12 @ 500mcg / week to 2000mcg a day, purely as just something to stick myself with between cycles, I have also done both SC and IM injections with no real difference exept some bruising with the high SC ones and I ran through a vein once.
You can use the oral supplements yet chances are more will be lost in digestion - although at high doses the oral counterpart will give you the same benifits.
quote:
--------------------------------------------------------------------------------
Maybe B-12 would be a way for me to get over my fear of sticking myself. Any legal way to get it?
--------------------------------------------------------------------------------
A good choice considering its cheap and easy to get - it is legal in most states and in most of canada, after all its a vitamin. If you have a friendly med associate a vitamin script wont raise much controversy either. It is also under $6 a vial.
quote:
--------------------------------------------------------------------------------
you mean to tell me that there are no bad sides to it??? - I have also heard that it can take the edge off steriod usage; aggression. don't know if it is true though
--------------------------------------------------------------------------------
Its a vitamin, plus the only sides associated with most water soluble b vitamins are diahreah and stomach discomfort. Doubtfull it could counteract the pschotropic effects of androgens although it does increase ones feeling of well being.
quote:
--------------------------------------------------------------------------------
is b12 for injections OTC? and shall ya inject it into the muscles or into the veins?
--------------------------------------------------------------------------------
Depending where you are it may be OTC, but its not hard to find online regardless and it wont get pulled.
Its only for I-muscle or subq (pinch&poke) not IV.