detroitbodybuildertigers said:
Ok I got about half of you saying to inject it IM and some sub-q. So which should I do and why
Bro, I dont think it makes a huge differnce either way. I shoot it intramuscular because this is the way I am more comfortable shooting it. Organon, Gonakor, and Serono all reccommend this written write on the boxes. I am not sure about the other brands like Ferring, or Steris
or Lepori for example, but I doubt many of them reccomend it Sub-q.
I mix mine in B-12 just for the added benefits of of the B-12. If I am going to be shooting something, might as well add some more benefits to it. And its pretty obvious to me that B-12 has more benefits than BAC water does. B-12 does nothing to effect the HCG.
In fact according to Dr.M there are much better things to mix your HCG with, such as Ringes Solution .. see below, a little blurb from him. I am personally going to use B-12 this time around for simplicity sake and the added health benefits
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Here is a blurb from one of the Doc's posts.
"Go to your local homecare and surgical store and find an IV bag of Lactated Ringer's Solution. This is what they infuse into you for a nutrient IV; it's pH balanced and buffered, it's got a great mix of ions to stabilize various protein structures (not why they're included in the first place, but it works out well for our purposes), and it's all around a good choice for peptide hormone rehydration for the purpose of storage.
Dissolve your hCG in Lactated Ringer's, then aliquot it into some slin pins (at whatever dosage you want to take). Pre-load ALL of your expected dosages into these slin pins. Pull back the plunger from the pin to make sure the liquid will have room to expand, and put all of the pins in the freezer (about -20°C is what a standard freezer holds at if not opened too much). When you need to take a shot, put the pin you need to use in the fridge to thaw... if taking a multi-day course of hCG, it works nicely... take out 1 pin on day 0, shoot that pin on day 1 and at the same time put 1 pin in the fridge for day 2, shoot one pin on day 2, put one in the fridge for day 3... etc.
If you try to freeze hCG in bacteriostatic water, it might not make it... but the comfortable mix of ions, sugars, and the buffered pH of Lactated Ringer's makes it a lot easier on the peptide hormone to store at 4°C or to freeze and thaw. That said, avoid repeated freeze/thaw cycles when using hCG from storage.
And some more info.
Lactated Ringer's (or even just plain Ringer's) have compositions which are generally more or less equivalent to your body's extracellular fluid. This is a great place for peptide hormones to be - if you understand protein structure, you'll understand why. Ions, buffered pH, osmotically balanced so that when it's injected it's not a shock to the contents when they either gain or lose water and/or solute... it's like a fucking day-spa for protein. Lactated or Plain Ringer's is like putting the peptide hormone in your body before putting it in your body.
It's like when buying new fish for a tank, instead of just dumping them in straightaway, you put the whole fish bag in the tank water and allow the temperature to equalize... it's a better transition for the molecule (fish) being carried.
More ....
Peptide hormones (as virtually all peptides are) are fragile. They require a certain 3-D conformation to work against their target receptor. This 3-D conformation is stabilized by various interactions which are disrupted easily in the presence of what biochemists refer to as denaturing conditions.
Organic solvents like BA and BB are both denaturing because they disrupt hydrophobic interactions within a protein and lead to its unfolding. Solutions like Ringer's or L.Ringers are much more stabilizing to a given peptide than organics. Water or Bac Water is better than organic solvents, but not if the peptide is to be stored for any length of time; it lacks a buffered pH, ions, and other factors which are vital to protein structural integrity in solution."