eddymerckx said:
nolavadex can trigger an upregulation in the progesterone receptors that, given a high estogen level, can increase the likihood of progesterone related gyno (from 19-nor compounds like tren/deca).
the better idea is to lower the estrogen overall with arom/armidex or use bronco or femara.
or add winny, and to a lesser degree proviron, to a cycle w/tren[/QUOTE
Can you explain the winny usage?
From Big Cats Steroid profiles...
"The specificity of Winny however, lies in how it counteracts estrogenic side-effects such as gyno and excess water retention. First of all it's a 5-alpha reduced substrate. 5-alpha reduction breaks the double bond between positions 4 and 5, which is required for conversion to estrogen via aromatase, the primary enzyme for the manufacture of estrogen in males. Because some of these compounds nonetheless show some affinity for aromatase they may have some use in blocking estrogen from other steroids they are stacked with. Wether or not Winny acts in this way is not entirely sure. What has been a popular point of discussion with stanozolol is its suggested anti-progestagenic effects. The theory goes that Winny can bind and compete for a position at the progesterone receptor much like Clomid of Nolvadex would at the estrogen receptor, thereby inhibiting progestagenic effects. Now, progesterone can aggravate estrogenic side-effects by agonizing estrogen and it does play a role in gyno."
http://www.bodybuilding.com/fun/catwinstrol.htm