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Fina - ed VS eod - the numbers
- Thread starter Zyglamail
- Start date
E2 said:
I agree..
ZYG- I don't think parent trenbolone has a half life of 24 hrs.. If you read the last line of the study you posted, "Thus, the disposition of 17 beta-trenbolone in humans
differs significantly from that in rats, which may have a bearing on the
toxicological evaluation of the hormone."
Parent androgens ususally have half lives of only a few hours. If the androgen has a 17 methyl group, the half life is further extended.. Example: Dbol half life is between 4-6hrs.. un-esterified Eq half life is only about 2hrs. (dbol is eq plus a 17aa). I belive the study indicates that rats do not pocess all of the androgen metabolism enzymes that humans do. Usually half-lives are shorter in rats, but androgens often undergo chemical alteration before excretion. That was the purpose for the radio-labeled trenbolone.
Anyway, if you re-made the graphs giving trenbolone acetate the proper half life of 24-36hrs, you will see over 100% jumps in blood concentration from ED to EOD injections! Incedentally, the values on the graph (300mg) are inactive, esterified TA.. You would need to subtract one day from the next for active androgen released.
I might also add... twice daily injections have a benefit that is not fully reflected in the mathematical (theoretical model). This is because home-made preparations are usually more concentrated and have a good portion of benzyl alcohol. First, the larger the concentration of the AAS in oil, the faster the diffusion rate. Second, if BA was used to make an unusually high concentration of AAS in oil, once injected, water in the body will extract out the BA leaving a large amount of steroid precipitated, and remaining steroid dissolved in oil.
This all means that 1) using BA to make a solution in oil that normally would not fit and/or 2) Making a high concentration of steroid in oil, can markedly accellerate the release rate. This really cannot be taken into account with a theoretical model since it would be quite difficult to quantify the in vivo effects of such preparations. If there were graphs made with this taken into accound, there would be even greater jumps in blood concentrations from ED to EOD injections.
This is the precise reason why I advocate making no more than 50mg/ml trenbolone acetate.
Great job on the graphs!! I would like to see you do another set, giving TA a half of 24-36hrs!
Andy
J2COOL2000
New member
great post bro very educational
Tren acetate half/life
<<The work is well done but i think you've highly over estimated teh half life of tren it is no where near 72 hours. >>
Yep Andy and E2 are correct. The half life of injectable Tren is only about 24 hous. No where near 72 hours. I was watching and wondering why it took so long for someone to bring this up.
<<The work is well done but i think you've highly over estimated teh half life of tren it is no where near 72 hours. >>
Yep Andy and E2 are correct. The half life of injectable Tren is only about 24 hous. No where near 72 hours. I was watching and wondering why it took so long for someone to bring this up.
A number of guys on the Fina board have been researching Trenbolone. As it turns out, there are a number of misconceptions about Tren.
One of these misconceptions is the half-life of Trenbolone Acetate which has commonly been believed to be 24-36 hours. Here is an abstract, posted by Zyg, on one study that indicates that Tren has a longer half-life than what has been assumed:
Disposition of 17 beta-trenbolone in humans.
Spranger B, Metzler M.
Department of Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Germany.
The urinary excretion and metabolic pattern of 17 beta-trenbolone, a synthetic anabolic Steroid hormone used as a growth promotor for beef cattle in several countries, has been studied in a human subject. For the separation of the metabolites of 17 beta-trenbolone, a reversed-phase high-performance liquid chromatographic method was established. The method was tested with metabolites obtained from incubation of 17 beta-trenbolone with rat liver microsomes. Fifteen metabolites could be well separated in one run by using a concave acetonitrile-water-methanol gradient. After ingestion of the tracer-labelled hormone at a dose of 0.04 mg/kg body weight 54% of the administered radioactivity was found in the urine after 26 h and 63% after 72 h. Of the urinary material 54% was present as glucuronides, which contained mostly 17 alpha-trenbolone, 17 beta-trenbolone and trendione. At least five other polar metabolites, presumably hydroxylated products, were found in smaller amounts, mostly in the unconjugated and sulphated fractions. Thus, the disposition of 17 beta-trenbolone in humans differs significantly from that in rats, which may have a bearing on the toxicological evaluation of the hormone.
One of these misconceptions is the half-life of Trenbolone Acetate which has commonly been believed to be 24-36 hours. Here is an abstract, posted by Zyg, on one study that indicates that Tren has a longer half-life than what has been assumed:
Disposition of 17 beta-trenbolone in humans.
Spranger B, Metzler M.
Department of Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Germany.
The urinary excretion and metabolic pattern of 17 beta-trenbolone, a synthetic anabolic Steroid hormone used as a growth promotor for beef cattle in several countries, has been studied in a human subject. For the separation of the metabolites of 17 beta-trenbolone, a reversed-phase high-performance liquid chromatographic method was established. The method was tested with metabolites obtained from incubation of 17 beta-trenbolone with rat liver microsomes. Fifteen metabolites could be well separated in one run by using a concave acetonitrile-water-methanol gradient. After ingestion of the tracer-labelled hormone at a dose of 0.04 mg/kg body weight 54% of the administered radioactivity was found in the urine after 26 h and 63% after 72 h. Of the urinary material 54% was present as glucuronides, which contained mostly 17 alpha-trenbolone, 17 beta-trenbolone and trendione. At least five other polar metabolites, presumably hydroxylated products, were found in smaller amounts, mostly in the unconjugated and sulphated fractions. Thus, the disposition of 17 beta-trenbolone in humans differs significantly from that in rats, which may have a bearing on the toxicological evaluation of the hormone.
Delinquent
Well-known member
so what's your bro's take on adding fina to a first cycle? I've seen some people say it's not advisable for a newbie to take one their first few cycles, but from what everyone is saying and then these results, why not?
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