EQ and 5AR

[lighter]

Am I correct that EQ is not an antagonist of 5AR which means it is similar to Deca in that it is light on the andro sides, meaning little or no hair loss, etc?

 

[krishna]

Boldenone also differs from testosterone in its ability to interact with the 5-alpha reductase enzyme. This is the enzyme responsible for forming dihydrotestosterone from testosterone, which is a much more potent activator of the androgen receptor. The 5AR enzyme is predominantly found in androgen target tissues such as the skin, scalp, prostate, pituitary, hypothalamus, and other regions of the central nervous system, and as such causes a notable increase in the androgenic potency of testosterone in these tissues. Although the 5-alpha reduction of boldenone (to dihydroboldenone) also results in the formation a more potent androgen, the C1-2 double bond on this hormone almost completely inhibits such interaction in the human body (2). Dihydroboldenone is likewise produced in small amounts at best in humans, allowing this hormone to be much less androgenic in nature compared to testosterone. On the plus side we see why athletes using boldenone injectables usually find them much more tolerable in terms of not promoting androgenic side effects such as acne, body/facial hair growth and hair loss. On the minus, of course we pay for reduced androgenic potency in terms of expected strength and mass gains (androgens are known to support neuromuscular functioning and development), which will be lower (though probably of higher quality) compared to that achieved with testosterone.

Basically, EQ has minimal interaction with the 5ar enzyme.