JohnnyWest said:What I gathered form your post is it raises endogenous testosterone levels if applied to stomach/legs and is suppressive to your HPTA if you apply to shoulders?
That doesn't make any sense, that's saying two completely different things. Either it's suppressive or it's not suppressive, if it's action is systemic like PP claims then it wouldn't have properties based on where you apply it.
PP or N2 can you clear this up?
Jonnywest,
What this means is that when you apply it to the shoulders it converts to testosterone before it even gets to the blood stream. So in that sense, your basically using a low dose test cream. This can obviously be suppressive.
We encourage PCT users to apply the product to areas on the skin that are not so concentrated with steroidogenic enzymes, such as the stomach and legs. This way the DHEA can get into the system to exert its positive effects on GH, IGF-1, cAMP, ect. While the original dermacrine works well for PCT, the effect of DHEA on endogenous testosterone production can be biphasic in that it may eventually have a suppressive effect on LH & FSH release by its eventual peripheral conversion to other androgens. (one of the reasons we recommend only 4 weeks use)
We’ve addressed the potential issue in the new version of “Dermacrine Sustain” by removing the DHEA/preg and increasing the dosage of the phyto-based AI’s. This will improve the products ability to increase LH & FSH even more, and serve more as a long-term solution.
Tshoot,
I hope Ive answered some of you questions here. I would suggest testing for both E2, E2 and testosterone if you plan on using the new Derma. You wont need to use anything with it, and one bottle lasting 26 days should be enough to get you back on track, especially considering your fast clearing esters.
-Pp