I believe so. Unfortunately, it's mostly genetics. I have crazy wheels and all I do is squat, but people said I had "oompah-loompah" legs before I ever squatted. But also, my whole workout is minimalist. Even in my weaker body parts, I have faith that contracting a muscle is all that needs to happen to hypertrophy that muscle. I don't believe in "shaping". So my workout is bench, squats, weighted chins, militaries, presses, curls, situps, calves, forearms. Keep in mind I may progress through max singles to 20set marathons with all this in the volume range, in every type of conjugated periodization. In addition to the scientific base, this has a grounding in tradition too. Arnold used this to build the bulk of his frame according to his autobiography, and Reg Park and Steve Reeves did this workout. As well as serge nubret only benched for his chest. So logic, science and experience all suggests squats are all you need.