For maximum effect, supplement 30 to 45 minutes pre - workout (or at least says most current research).
As with most drugs, the side effects of taking ephedrine based products are normally dose related. In over - the - counter products which contain ephedrine, the dose is not harmful. Generally, if you have personally heard of any stories about the ill side effects of ephedrine, it is more than likely that the individual was consuming far beyond the recommended dose of approximately 100 milligrams a day - and with pro BB's, you can guarantee they probably tripled this amount. so, i cant really say for certain if it is dangerous. ephedrine has the potential to increase heart rate as well as blood pressure. That said, individuals with a weak heart, or a history of heart problems may want to avoid taking ephedrine - but once again those individuals with heart problems who have reported incidents of discomfort while using ephedrine based supplements have once again been abusing the drug (at least more than likely).
matt