I would never do a tren cycle without test. Never.
As for dosing, you could get results from 75mg/eod, however best results come from every day injects. Most do 75-150mg/day for tren. E2 has gone up to 260mg/day of tren for something like 12 weeks.
I think the 'it's bad for your liver and kidneys' thing is myth, but nobody is really sure. I just have never heard of anybody having any problems from it, and most do not do too much for their liver or kidneys(I haven't).
I go 6 days/week for my injects. That way I get one day free. I feel like a pincushion, but fina is just amazing stuff.