Am or Pm injects for HGH?????

[syd black]

I know this has been brought up b4 but I have recently talked to a few guys that I consider to be pretty smart when it comes to growth and I am getting different answers.

Is there anything new in regards to this.
Am or Pm injects or does it not really matter?

 

[Big BX]

Twice a day injections gave me very nice results. I hit it before workout and before bed, 3IU's each time, everyday. I have never done morning injections.

 

[DarkMoon]

I do them whenever I get the chance. But Mostly at PM I never do AM

 

[Spidey]

Natural HGH production occurs mostly at night so it might be better to do AM injects to avoid supressing natural production at night.

 

[NorthNPrincess]

Morning.....You don't want to throw yourself into a diabetic coma and be asleep when it happens!

 

[syd black]

Morning.....You don't want to throw yourself into a diabetic coma and be asleep when it happens

Youve lost me here, what does growth have to do with diabetes?

 

[NorthNPrincess]

Well, HGH stimulates the liver to produce IGF-1 (insulin like growth factor) Insulin helps with the uptake of sugar....IGF-1 is the antagonist of this. You don't uptake sugar. It may cause an increase level of glucose in your blood .....you may "dump" glucose in your urine.....Blood sugars too high or too low can cause problems. You are messing with the endocrine system!

 

[syd black]

Are there any cases of anyone getting diabetes from growth?

 

[Triggerman2003]

syd black....I have not heard it yet, but it might. Now for the AM, PM thing........I heard from both ways...my personal source told me to do the night time before bed and I did with no problem, that is what he does. Then the other day I heard do them after you get up....I am thinking WTF? So later I did that and no problem there either. But I would like to see literature on proper times of injection for maximum effect myself so I won't be going WTF?

 

[NorthNPrincess]

Good Read for you.....

Growth hormone can be given either substaneously or by intra-muscular injection with equal therapeutic activity. Subcutaneous administration is now used almost exclusively because intra-muscular administration is fraught with an increase in side effects without any additional therapeutic benefit. The reason for this has to do with the biofeedback mechanism for growth hormone. Most of our natural pituitary growth hormone secretion occurs at night during deep stages of sleep. Injecting growth hormone at night raises the serum level of growth hormone precisely during the time the pituitary is scheduled to become active. This high serum level of growth hormone from the injection can suppress our natural pituitary function by negative feedback. We then not only lose the benefit of our own endogenous growth hormone, but also run the risk of surpressing the pituitary, thus making it "lazy". For the most part, the pituitary has completed its function and is at rest by 5 a.m. Therefore injecting after awakening in the morning results in injecting "on top of the peak" of endogenous (our own) growth hormone, so as not to suppress the pituitary. By the time the pituitary is ready again for its nighttime activity, the growth hormone given in the morning injection has been completely metabolized. This eliminates the risk of pituitary suppression.