I have them all and the V kicks in about 15 to 20 min later. You will get this flushed face feeling and then it is working. I keep the V for the last minute hook up and the Cialis for the guaranteed weekend knockaround. Both give me wicked headaches and a serious stuffy nose but it is all worth it to hit it all night and be harder than final jeapordy !!! They all work, just depends on your situation.