Could Accutane be estrogenic in general or aid estrogen receptors in certain body tissues such as bone?
This is from wiki on accutane:
In FDA's medication guide for Accutane it says "Accutane may stop long bone growth in teenagers who are still growing".[44] Several reports states that spontaneous premature epiphyseal closure can occur in acne patients receiving recommended doses of Accutane.[45][46][47][48][49][50][51][52] Since the age until complete ossification of bones varies between individuals (17–20 years for upper limbs, 18–23 years for lower limbs)[53] and since many are prescribed Accutane in their late teens, when growth still occurs but has begun deaccelerating, there is a risk for a gray zone with people being affected without knowledge about it. The effect of multiple courses of Accutane on epiphyseal closure is unknown.