i ran about 750mg/wk all thru the course of my accutane cycle, and my vales always come back either normal, or close enough to normal to be considered by my doc in the 'safe' range for a person on accutane -- and i also would have 3 or 4 drinks every friday/saturday nite at work...just make sure you drink plenty of water, and dont drink any alcohol for about a week before you get ur bloodwork done and you'll be fine.