I know at least 3 people that have used low dose T3 succesfully (aside from the issue of cosmetics in bodybuilding), and 2 of the 3 have been able to come off succesfully without any hampering on their thyroid. One good friend of mine has still stayed on for the past few years and don't know when he will get off. He swears by it, just wondering if he will be doing htis for life.