Yeah side effects could be too a little too heart unfriendly with the thermo and stimulant. I think you can do the Anti Cortisol/Therm/Thyroid though. If you could make it, that particular combo, well, that would just be the shit!
Look at Suppress C, Erase, and a few others for Cortisol reduction
Look at Alpha T-2 for thyroid control. They use two ingredients which are now being used by all the other competitors.
Look at Forged Burner, Hot Rox, Meltdown, Redline, etc...for Thermogenic control
There's some starting points.