with SSRI's, DRI's and NRI's its really a guessing game whats going to work. Individual neurochemistry is not discernable by symptoms, though it does give an idea of where to start.
with these drugs you will find that many people have VERY STRONG opinions both for and against them. they should be looked at as an addition to therapy and behavioural modification, taking them generally just makes the symptoms less apparent or more manageable, IDEALLY so that you can take the steps needed toward managing without them.