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Why this grade?

Well, first of all , that isn't exactly a scientific evaluation. Anybody can write anything.

Secondly, the 2 are very similar and sometimes you can't go by what's on paper. People simply react differently to different drugs. For example, Nolva and Clomid are similar in structure and do essentially the same thing, yet both drugs have the same (negative) effect on me. Meanwhile, others will say one works great for them while the other sucks. Sometimes you just have to go with what "feels" better.

Adexx does have the advantage of lowering SHBG and actually improves sex drive (unless dosages get too high). And although dexx is powerful, Aromasan is even stronger (which some people like) but an overdose can actually remove all estrogen from the body leaving it at risk of a heart attack. And by that I don't mean taking an excessive amount, but a prescribed amount.

Still, it's spitting hairs. For me, dexx is best.
 
Nelson Montana said:
Well, first of all , that isn't exactly a scientific evaluation. Anybody can write anything.

Secondly, the 2 are very similar and sometimes you can't go by what's on paper. People simply react differently to different drugs. For example, Nolvaldex - tamoxifen citrate - and Clomid are similar in structure and do essentially the same thing, yet both drugs have the same (negative) effect on me. Meanwhile, others will say one works great for them while the other sucks. Sometimes you just have to go with what "feels" better.

Adexx does have the advantage of lowering sex hormone binding globulin and actually improves sex drive (unless dosages get too high). And although dexx is powerful, Aromasan is even stronger (which some people like) but an overdose can actually remove all estrogen from the body leaving it at risk of a heart attack. And by that I don't mean taking an excessive amount, but a prescribed amount.

Still, it's spitting hairs. For me, dexx is best.

People do react differently; arimidex gives me major erectile disfunction even if I'm on a shitload of test. Too much letrozole will wipe out my libido but at least I can still get wood.
 
Nelson Montana said:
Well, first of all , that isn't exactly a scientific evaluation. Anybody can write anything.

Secondly, the 2 are very similar and sometimes you can't go by what's on paper. People simply react differently to different drugs. For example, Nolvaldex - tamoxifen citrate - and Clomid are similar in structure and do essentially the same thing, yet both drugs have the same (negative) effect on me. Meanwhile, others will say one works great for them while the other sucks. Sometimes you just have to go with what "feels" better.

Adexx does have the advantage of lowering sex hormone binding globulin and actually improves sex drive (unless dosages get too high). And although dexx is powerful, Aromasan is even stronger (which some people like) but an overdose can actually remove all estrogen from the body leaving it at risk of a heart attack. And by that I don't mean taking an excessive amount, but a prescribed amount.

Still, it's spitting hairs. For me, dexx is best.

Nelson is incorrect here, they do NOT do the same thing, Nolvadex blocks estrogen receptor sites in SOME tissues, Clomid stimulates Leutenizing Hormone (LH) to stimulate the testes back into production.

Cheers
 
nydj66 said:
People do react differently; arimidex gives me major erectile disfunction even if I'm on a shitload of test. Too much letrozole will wipe out my libido but at least I can still get wood.

i just discovered that with femara/letro last week---i was not sure if it was the test or the femara but i went searching through drawers looking for some leftover proviron (wife is trying to get preg so i have to put out--would rather sleep)
 
Letro is commonly known to give loss of libido to many users.
A lower dose will usually still give the benefits needed after tapering down, without such an impact on libido.
Cheers
 
littleguy said:
Nelson is incorrect here, they do NOT do the same thing, Nolvadex blocks estrogen receptor sites in SOME tissues, Clomid stimulates Leutenizing Hormone (lh - leutenizing hormone - ) to stimulate the testes back into production.

Cheers

Well you are partially correct littleguy. Nolvadex and Clomid both can stimulate LH. Both are synthetic estrogens in the body and attach themselves to estrogen receptor sites mainly in breast tissue. Since the estrogen from aromatization can't reach those receptors since they are blocked, gyno is prevented or at least minimized.
 
st8grad said:
Well you are partially correct littleguy. Nolvadex and Clomid both can stimulate lh - leutenizing hormone - . Both are synthetic estrogens in the body and attach themselves to estrogen receptor sites mainly in breast tissue. Since the estrogen from aromatization can't reach those receptors since they are blocked, gynecomastia is prevented or at least minimized.

NOPE
Clomid mainly binds in the brain. The H [PTA] is where it binds most that's why it stimulates LH/FSH.
Nolva has no such mechanism and does bind mainly in the breast tissue.
Cheers
 
littleguy said:
Nelson is incorrect here, they do NOT do the same thing, Nolvadex blocks estrogen receptor sites in SOME tissues, Clomid stimulates Leutenizing Hormone (lh - leutenizing hormone - ) to stimulate the testes back into production.

Cheers


No, I said they're similar in structure.

I'm well aware that Nolvaa is site specific but the side effects are often very similar. Whereas Clomid is a very "hit or miss" drug, Nolvaa is very good at preventing gyno (better than Clomid) but not good for much else.

As for stimulating LH, Hc G does this much better than Clomid. Now before you get technical on me it should be noted that Hc G MIMICS LH. But the end result is the same -- to "start the engine" so to speak. Problem is, where HcG almost always works, Clomid often fails. Both are temporary solutions and the body must start working on its own which is why it's imperative to use natural pathways and supps can help. But to get over the hump, Hc G and dexx is a better choice more often than not.
 
Not meaning to carp, since, as you say, HC G acts as L H, but clomid stimulates your own production of L H.

By acting as L H, HC G stimulates your gonads to get them quickly along the path of producing again. Clomid works further up the chain.
 
littleguy said:
NOPE
Clomid mainly binds in the brain. The H [PTA] is where it binds most that's why it stimulates lh - leutenizing hormone - /FSH - follicle stimulating hormone - .
Nolvaldex - tamoxifen citrate - has no such mechanism and does bind mainly in the breast tissue.
Cheers

Again, not correct.

Nolvadex will also block estrogen receptors in the hypothalamus and stimulate FSH, LH, and testosterone production through the same mechanism as clomid.

Nolvadex is better than clomid at blocking estrogen receptors in breast tissue which is why it's used to treat breast cancer.
 
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