I'm on accutane right now, 215-220 lbs, third month so far and it's like night and day from what I was like before. I've always had really oily skin and it's dried me up like a sponge on a hot sidewalk. I started taking 40mg a day and now I am up to 60mg a day. I'm doing the generic thing and they only have 10mg and 20mg tabs to I take one of each, two times a day. As someone said before, about the cracking lips, about five minutes after I put chapstik on, it's right back to cracking and peeling. If I go for more than an hour or so (when I'm awake, for some reason sleeping isn't a big deal) my lips will actually crack so deep they will bleed. It sucks but worth it in my book. I'm going through a doctor and she has me get my blood checked every month before she'll cut me a new prescription. We'll see how it blows up after my first cycle just around the corner! =)