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napsgeargenezapharmateuticals domestic-supplypuritysourcelabsUGL OZUGFREAK

what to use in replace of pct

macrophage69alpha said:
1.men dont have a uterus.
2. agree that tamoxifen has toxicity issues, just disagree with your explanation as to why, it also has effectiveness issues. However while recognizing toxicity issues one must also consider that low dose, short term, usage is unlikely to present these issues.
3. clomid is proven effective in restoration of the HPGA- the fact that it is a teratogen is irrellevant- unless you are pregnant. the emotional sides of clomid are generally mild with no frontload.

I had never used clomid either, was worried about the sides and shit, stuck to nolva. Last cycle used HCG, AIFM and Clomid and rececovered awesome and kept 10 lbs on the 17 I gained.
 
mm107 said:
Dermacrine, the new sponsor topical

Out of all honestly, im usually skeptical, so when i tried AIFM i was amazed at how it kept me dry. AIFM is great for keeping your estrogen under control.

But the new company Dermacrine, i emailed them, got a bottle, and they asked me to run it w/o nolva/clomid. I emailed them back and asked if this was safe and how effective. Here was the reply.
ya i am trying it to.and they seem pretty confident. confident enof too pay for the test to.so I am thinking it must be good.
 
Primordial Performance said:
Macro,

The rats using 4-OHA tamoxifen may have escaped liver cancer, but unfortunately they probably didn’t escape uterine cancer -- Being that 4-hydroxy tamoxifen is the primary cancer cancer causing metabolite of tamoxifen in the uterus.

Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: Comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen
Deena N. Pathak, Krisztina Pongracz, and William J. Bodell
Carcinogenesis, Sep 1996; 17: 1785 - 1790

Activation of the Tamoxifen Derivative Metabolite E to Form DNA Adducts: Comparison with the Adducts Formed by Microsomal Activation of Tamoxifen
Krisztina Pongracz, Deena N. Pathak, Takemichi Nakamura, Alma L. Burlingame, and William J. Bodell
Cancer Res., Jul 1995; 55: 3012 - 3015.


Teratogenic effects of clomiphene, tamoxifen, and diethylstilbestrol on the developing human female genital tract.
GR Cunha, O Taguchi, R Namikawa, Y Nishizuka, and SJ Robboy
Hum Pathol, Nov 1987; 18(11): 1132-43.


Either way, we have to be careful when interrupting results from a rat studies. Remember, rats have a notable difference in their P450 gene characterizes and a pleiotropic drug such as tamoxifen is going to complicate things even further. Besides, debating over which tamoxifen metabolite has the most carcinogenic effects in whatever part of the body seems moot to me. I think it is clear that nolvadex is a toxic drug.

As far as clomid goes, I don’t think we need a study with male bodybuilders to realize it can cause problems. I personally wouldn’t want to use a substance with known tetrogenic effects. Besides, the last time I was on clomid, I had a non-existent sex drive and I cried about 4 times while sitting through “The Notebook”. That was the deal breaker for me.

-Pp
fuck I like this new guy around here its going to make for some fun I can see it now.
 
needtogetas said:
fuck I like this new guy around here its going to make for some fun I can see it now.



Me too :Popcorn:






-BRR
 
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