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Wellbutrin and Stimulants

marqui77

New member
I have been wellbutrin for a few months now and I decided to start taking fat burners this week. The combination made me so dizzy, and I have used fat burners and clen in the past without any problems. I took them for 2 days, then switched to clen...I lasted one day. It seems any combination with wellbutrin does'nt work well for me. Anybody else on wellbutrin experience this problem?
 
marqui77 said:
I have been wellbutrin for a few months now and I decided to start taking fat burners this week. The combination made me so dizzy, and I have used fat burners and clen in the past without any problems. I took them for 2 days, then switched to clen...I lasted one day. It seems any combination with wellbutrin does'nt work well for me. Anybody else on wellbutrin experience this problem?

DUDE, WTF?

Wellbutrin inhibits the reuptake of epinephrine. What do stimulants do? They increase the production of epi and norepinephrine. Taking stimulants like clenbuterol with wellbutrin sounds like a great way to die....
 
marqui77 said:
Wellbutrin causes an increase in norepinephrine, serotonin and dopamine. I am not an expert on this...this why I wrote what I did. On the manufacturer insert it says nothing about taking wellbutrin with stimulants.. http://us.gsk.com/products/assets/us_wellbutrinXL.pdf

Wellbutrin doesn't increase the production of, but essentially blocks the exit of epi and norepinephrine from the synapse of the brain. (hence the term reuptake inhibitor.) Therefore, all of the epi and norepinephrine that is present is allowed to bind to receptors.

When you take a stimulant that drastically increases the production of the two, you will be very much over-simulated. Because it isn't exiting the synapse like its supposed to normally.
 
what POANTREX mentioned is correct... add to this the fact the wellbutrin is used to help people stop smoking because it is actually considered one of the more stimulating psychopharmaceuticals to begin with. Adding clen to the mix is a def. NO-NO
 
Adding clen to the mix is a def. NO-NO
I found this out this out the hard way, ephedra is also a bad mix. Caffine is the only thing that mixes without any problems, but I would like to use a fat burner that will work well. Most fat burners, I realise are'nt going to mix.
 
marqui77 said:
I found this out this out the hard way, ephedra is also a bad mix. Caffine is the only thing that mixes without any problems, but I would like to use a fat burner that will work well. Most fat burners, I realise are'nt going to mix.

Hell, wellbutrin by itself is a fatburner.
 
True on what poantrex said.
Wellbutrin, while inhibits NE reuptake pump also decrease NA-neuron firing which could be modulated/upregulated by either an alpha-antagonist or beta-agonist (clenbuterol) which would lead to a rapid accumulation of NE. Accumulation and binding of NE in the peripheral systems leads to bad side-effects, like hypertension, restlessness, dizziness, etc.

But it also depends on tolerance - I am taking Wellbutrin concurrently and have taken it before and well tolerated most of the stimulants (recretional including) except yohimbine (alpha2-antagonist) and synephrine (alpha1-agonist).
 
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