Wellbutrin and Stimulants

[junk]

True on what poantrex said.
Wellbutrin, while inhibits NE reuptake pump also decrease NA-neuron firing which could be modulated/upregulated by either an alpha-antagonist or beta-agonist (clenbuterol) which would lead to a rapid accumulation of NE. Accumulation and binding of NE in the peripheral systems leads to bad side-effects, like hypertension, restlessness, dizziness, etc.

But it also depends on tolerance - I am taking Wellbutrin concurrently and have taken it before and well tolerated most of the stimulants (recretional including) except yohimbine (alpha2-antagonist) and synephrine (alpha1-agonist).

Hey Juve,
always pleasure reading your posts

Are you using the Wellbutrin as an anti-depressant ? Along with an SSRI maybe? Or maybe for appetite supression ?

I've been using Provigil at 200mg twice a day and all I can say is WWOO Modafinil is some good too good to be true shit (though extremely expensive at high dosages). It's main advtage is instant effect (1 hours) as opposed to other options of 2-4 weeks. Just curious about your experience.. Did you happen to compare the two ?

JUNK

 

[juve]

Hey Juve,
always pleasure reading your posts

Are you using the Wellbutrin as an anti-depressant ? Along with an SSRI maybe? Or maybe for appetite supression ?

I've been using Provigil at 200mg twice a day and all I can say is WWOO Modafinil is some good too good to be true shit (though extremely expensive at high dosages). It's main advtage is instant effect (1 hours) as opposed to other options of 2-4 weeks. Just curious about your experience.. Did you happen to compare the two ?

JUNK

Thanks for a concern
I am taking Wellbutrin as an adjunct to my anti-'manic depression' regimen and as an attempt to stay away from rec drugs.
I completely agree on Modafinil - I have like a lifetime supply of it. Sometimes take up to 600mg a day - one of the better CNS-preferrential stimulants ever procured.

 

[poantrex]

I hope nobody here self medicates with anti-depressants. Using any type of anti-depressant will cause sometimes permanant changes in receptor affinity for seratonin, dopamine and (nor)adrenaline - and ceasing their use will result in debilitating fatigue and depression because the body has become dependant on it. Wellbutrin isn't as bad in some people...although some report dependance on it. but disconuing SSRI use will cause massive depression most of the time.