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thoughts on frontloading long esters
- Thread starter juggy54
- Start date
you would think it would help--i mean get to the planned peak sooner, but all i have ever heard is bros claiming it either did nothing (maybe some sort of response to too much so its excreted) or other reporting the worlds worst sides inside of a week---so i do not know the medical reason, but the bro-ological is that it in not a good idea.
hence d-bol kickstarts.
hence d-bol kickstarts.
needtogetaas
New member
I never do it. Just use a jump start compound. Same effect you are looking for yet it works.
"The theory is that steady state concentration (and therapeutic effect) will be reached faster. But this doesnt work for AAS. Why? BC steady state concentration is usually achieved after four half lives. The half life for long esters is days and weeks.
Assuming T1/2 of TestEnanthate is 10 days, then it won't be reached until 40 days. Also, of the several recognized pathways of action, the MAIN one we are interested in, the anabolic component of protein synthesis (transcrption/translation, etc.) takes a good two weeks to occur. No amount of loading dose is going to increase the speed of this process.
The loading dose = the volume of distribution x the desired concentration (i.e. the concentration at steady state).
If you run the numbers for a 500mg weekly dose:
Loading dose = usual maintenance dose / usual dosage interval x kel (t1/2/0.693). This comes out to about 1 gm.
But as explained above, you will get all the risk and none of the benefits.
It does work for faster acting compounds however, thus you may frontload with single esters or orals."
from my boy todoveritas. he knows his chemistry & biology.
Assuming T1/2 of TestEnanthate is 10 days, then it won't be reached until 40 days. Also, of the several recognized pathways of action, the MAIN one we are interested in, the anabolic component of protein synthesis (transcrption/translation, etc.) takes a good two weeks to occur. No amount of loading dose is going to increase the speed of this process.
The loading dose = the volume of distribution x the desired concentration (i.e. the concentration at steady state).
If you run the numbers for a 500mg weekly dose:
Loading dose = usual maintenance dose / usual dosage interval x kel (t1/2/0.693). This comes out to about 1 gm.
But as explained above, you will get all the risk and none of the benefits.
It does work for faster acting compounds however, thus you may frontload with single esters or orals."
from my boy todoveritas. he knows his chemistry & biology.
GUARDIAN said:
uhhhh, yea, that is what i was going to say.....x over steady state minus the weight on 8and20s quads on the moon + the price of needto's killer cookbook ----
i have been unsmarted again by the guardian--
start off 4 weeks of anadrol 50 or dbol. That'll kick your ass before you hit the long-esters.
the_alcatraz said:
+1.
use an oral and do not inject crazy amounts of gear to "frontload". That sounds like a stupid thing to do.
Honestly, once you inject your first ml of gear, it goes to work. The gains aren't visible but they are in process almost immediately.
Orals just show those results in a very short period of time. 30mg of dbol does the trick for me.
dabuffguy said:
It takes at least 100mgs of anadrol 50 ed to do the trick for me
dabuffguy said:you likes dat 'Drol.
I haven't used it yet. I am really curious to try it but I'm not seeing the need to try it just yet.
Nothing comes close to the power / strength gains I get on anadrol bro...that shit makes me think I'm superman
sensational
New member
the_alcatraz said:
In my experience, it is a rare person who can deal with 'drol!
But those who can swear by it.
As far as front loading, it doesn't seem to offer any pharmacological advantage.
sensational said:
it's very toxic on the liver, but I wouldn't say rare...I know a lotta my friends use it as well....
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