Please Scroll Down to See Forums Below With too much time on my hands today I wondered... WHY can't they make a substance that can cause the body to produce MORE androgen/anabolic receptors? Or make the ones we have be more receptive????
Things that make you go Hmmmm???
- Thread starter ArizonaFeeds
- Start date
PBR
New member
Ive been told that doing AAS cycles over the years actually does make up more receptors....I DONT KNOW if there is any TRUTH to this claim or not.....it was thought years ago that methandriol dipropinante did this very thing , but apparently that was a bogus claim.....GOOD QUESTION.....I often wondered if using GH helped along these lines also?????I wish we would find an alternative route for building muscle mass....sure would be nice to give up AAS and all the post cycle therapies.....you know???
liftsiron
New member
Yes methandriol dipropinante was used widely for this purpose, but is now considered pretty much worthless. The closest drug that comes close to matching these claims, works not by opening or creating more receptors but by lowering SHBG and allowing more free test to work. This would be proviron of course, its adds a definite boost to any cycle. And its effect on libedo are legendary.
D
Deleted member 33117
Guest
Actually research has now shown that AR's upregulate to accomidate blood serum testosterone levels. The fastest way to upregular your receptors is to take high doses of test. In recent studies, subjects given 600 mg of test enathate a week had roughly twice as many androgen receptors as subjects given 300 mg per week. Come on guys, this is suppost to be common information now.
If they could do that they could cure baldness, or for that matter, almost anything else.
In regard to making more T mre available, that's exactly what is the premise behind the product "Unleashed." It's based on the Proviron concept liftsiron mentioned. All these supp companies have been trying to make a psuedo -steroid (and failing miserably) when the answer is already available -- lower SHBG and make more T "active". It's very simple really, and very effective. I'm just anxious to get more of it. (Hold up with production). Soon.
In regard to making more T mre available, that's exactly what is the premise behind the product "Unleashed." It's based on the Proviron concept liftsiron mentioned. All these supp companies have been trying to make a psuedo -steroid (and failing miserably) when the answer is already available -- lower SHBG and make more T "active". It's very simple really, and very effective. I'm just anxious to get more of it. (Hold up with production). Soon.
D
Deleted member 33117
Guest
PBR said:
Actually, its not years, its weeks. With fast acting esters or orals (human studies have been done on anavar for this) upregulation occurs in less than one week.
is proviron Schedule III?? Or is it easily obtained?
D
Deleted member 33117
Guest
AF, proviron is considered to be an anabolic steroid for legal purposes. Also, it has never been approved by the FDA in the US, so you'll have to get it from overseas illegally.
I never bought the "up-reglation" theory. It just doesn't make sense. How can a drug become increasingly more effecive? If that were the case, experienced users would need less and less. That's just not the case. Psuedoscience poppycock mixed with wishful thinking IMO.
PBR
New member
nelson...I agree....if this were true, a little AAS would go along way and dosages would be half to a quarter to what experienced users are injesting...I will say one thing on this note: I have noticed that when I start a new cycle, I show signs of being "ON" in a matter of DAYS, where as it used to be weeks before I would feel anything and wondering if my products were real or not....and it can be anything also, any type of AAS will show action within days of injesting for me now....what would you attribute this to??? (sensitivity)...thanks for your input and time.....Nelson Montana said:
There is a certain sensitivity issue and AAS aren't alone in that. Somehow the body recognizes the presense of the drug quicker. This is very noticable with pot. The first few times people try it -- nothing, then after the third time...BAM. But that still doesn't discount the tolerance factor. The body will always try to remain in homeostasis and attempt to build up an immunity to any outside influence.
D
Deleted member 33117
Guest
Nelson, I would agree if we were talking theory... I don't like the shitty pseudo-scientific garbage proposed by many bodybuilders with no real scientific background. I was refering to what scientist have discovered about AR upregualtion based on dose in double-blind studies. AR upregulat based on dose, and very rapidly. Of course they haven't tested anything over 600 mg of test per week as of yet.
ung, I think compairing androgen activity in the body to smoking pot is a very poor comparison.
ung, I think compairing androgen activity in the body to smoking pot is a very poor comparison.
BodyByFinaplix said:
Yeah, i know.. bad comparison, and out of line, didnt mean to spoil a good thread.
Have heard of few who started to loose muscle on a few hundred mg`s a week after a while on, and they should grow on that dose.. Either its downgrading of receptors, or the body trying to remain in homeostasis, it seems like you still need more after a while on, but the thread is interresting!
D
Deleted member 33117
Guest
I think the reason for that is the body trying to stay in homostasis. Muscle growth requires anabolic activity to exceed catabolic activity. Once the receptors upregulate to accomidate the higher test level (and science nows tell us they do this, so until new evidence shows up, and it could, that shows otherwise, should we not say they probaby do?), the higher level does NOT become more anabolic. As you grow larger, your body does become more catabolic, so it becomes more difficult to gain new size. Eventually if you stay on the same dose (and do not find another means to increase anabolic activity or reduce catabolism), and have surpassed your natural limit, of course you will stop growing, once catabolic activity = anabolic activity.
Ung, all is forgiven, and you are correct about pot, as anywho who has smoked it can attest too. The same is true of alcohol.
Ung, all is forgiven, and you are correct about pot, as anywho who has smoked it can attest too. The same is true of alcohol.
nadr7891
New member
IMO if drug companies wanted to focus on creating kinder, gentler and more effective steroids (or supplemental drugs to make existing steroids work better) they could easily do it. these are very old drugs. but, there's more money in other types of drugs and steroids carry a stigma because of so much abuse. so they spend their R&D on other shit.
PBR
New member
Which leaves a great big door for smaller companies and or scientific personnel to develope new avenues....the money that could be made- would be staggering.....yes" they" carry a stigma...but only in the open forum....professionals in all aspects of all sports know that a new discovery would be of biblical proportions...not to mention the commercial/ retail arenas....maybe some day.....nadr7891 said:
Similar threads
