i guess i disagree (based off this theory, which i need to research further)...
high doses of AAS cause multiple growth pathways, other than simply stimulating androgen receptors (which is the only growth mechanism for SARMs). the whole class 1/class 2 theory is based around the propensity to bind to receptors, though... however, i agree that you have a valid point, as i have no idea how tightly Ostarine binds to the receptor (as opposed to Anavar, which is known to bind rather weakly). as long as Ostarine binds more effectively, then Anavar can do other growth producing things in the body...
and, i was apparently wrong about Anavar binding weakly...
i found this excerpt on this site:
"Anabolic Steroids achieve their effects on hypertrophy through different mechanisms,and as such are classified into two different categories,class-I and class-II compounds.I will explain which ones work through which pathway,and how to effectively combine opposing groups to maximize potentiation of one another for explosive growth....
Class-I-These are steroids who's primary influence on anabolism is achieved through aggressive binding and activation of the androgen receptor...Examples of potent class-I's are-Deca-durabolin,primobolan,equipoise,oxandrolone...
Class-II-These are compounds with potent activity independent of A/R binding/activation,and their activity has been monitored in neuron's,microsomes,mitochondria,etc...Examples of potent class-II's are-Anadrol,Dianabol,winstrol,Fluoxymesterone...
Then we have steroids that are potent combination steroids all by themselves(meaning they display influences on growth through both class-I and II activity,and thus are very effective as'stand-alone'anabolic agents as well as forming the 'base' of most steroid stacks)....Two compounds possess this unique characteristic-Trenbelone and testosterone.Either of these two steroids should form the base of most users stacks,as the cover both A/R and non-A/R mediated mechanisms,and adding to them with either a class-I or II will only potentiate that particular mechanism towards muscular hypertrophy...
Now that we're aware of which compounds work through which mechanism,how do we combine them effectively to maximize each one's potential?As explained above,testosterone and trenbelone should form the base of any serious steroid stack,but great effects can be had by combining single mechanism steroids from opposing classes....Examples of this type of synergistic combining could be(but are not limited to)"
and i found this elsewhere:
"Class I : binds to androgen receptor
Trenbolone
Oxandrolone
Primobolan
Masteron
Nandrolone
Boldenone
Class II : Does not bind to androgen receptor
Dianabol
Anadrol
Winstrol (possibly somewhat mixed)
Mixed
Testosterone
Probably Oral Turinabol , but I haven't done adequate trials with it."
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