SARM's, Science and "Bro-Science"

[dwkestrel1]

All chemicals have potential side effects on physiological functions. Side effects are common. Rather than a response of "I've never heard of that", I think it would be enlightening to have people list any negative side effects to specific SARM's beyond the well-documented ones (vision issues at high doses of S4. Don't bash a sponsor in public but this would allow PM's amongst forum users. I'll start.....leg rashes and back pumps (kidney issues) and water retention (5-6 lbs)at 25 mg ED MK-2866 in my test rat. No other compound being used. I hope the moderators see the value in this discussion.

 

[tha_Waco_kid]

I get the back pumps on osta too. I can usually counter them with an obscenely large amount of water intake daily. But otherwise they come and go throughout cycle. 25mg daily

 

[RickRock13]

My rats have never encountered any negative side effects from Ostarine at 25mg ED, and only minimal vision sides from S4 at up to 100mg per day. I used Sarmssearch, so quality of SARMS could possibly be a factor in presence of side effects as well.

 

[bigbassturd]

I'm with Rick on this one..

Never had a single problem running sarmssearch products, even at high doses

 

[notjake11]

I've been on Osta at 25/day for nearly four weeks and (1) no back pumps; (2) if anything have shed water rather than retaining it. It sounds like you may not be consuming enough water - could cause both of those issues.

 

[dylangemelli]

Bro science because an answer you got is that noone has seen those issues? do a google search on it and look for articles, instances etc... of this and good luck finding it? how is there any bro science involved in that... if you have a science question, ask away... Nothing is 100% on anything that we take... what works for 95% of people leaves a 5% ratio that may have other effects... there's no SCIENCE or BRO SCIENCE in that whatsoever... that's just the difference in body types... that's why things are never 100% guaranteed because body makeup cannot be pre determined... I have never heard of the problems you are having with sarms, especially ostarine which has had very few instances of any side effects... any side effects that it can bring generally occur when people abuse the dosage and exceed 25mg... IS IT POSSIBLE that 25 may be a bit much for you, or that your body is rejecting it entirely... YES THAT'S POSSIBLE... is it a normal thing, NO ITS NOT... It could be come down to quite a few things... You never mentioned where you bought it, what your history of certain conditions are, allergies, etc... You were never given an eval to determine any of these things... So before you go around making asshole condescending comments, take a look at yourself and what you are writing first... I know that I help so many people daily, ON MY FREE TIME, and continually GIVE to this community... I and many others are not getting paid for this... I have a masters degree for a reason, because I put in my time into studies, etc... This is WHAT I DO FOR A LIVING... as much as I TRY TO FREELY GIVE, I don't have time to GIVE SCIENTIFIC answers on a daily basis to every question... I try to sum it up the best I can on each question... Do you realize I get nearly 75 pm's A DAY and I ANSWER EVERY LAST ONE OF THEM, not to mention all the threads I go through to help... WHO DOES THAT ON ALL THEIR FREE TIME? NOT MANY... Instead of being unappreciative and coming acorss as a jerk, maybe next time you can be appreciative of FREE HELP and just ask for a bit more explanation if your not satisfied with an answer...

 

[dwkestrel1]

Bro science because an answer you got is that noone has seen those issues? do a google search on it and look for articles, instances etc... of this and good luck finding it? how is there any bro science involved in that... if you have a science question, ask away... Nothing is 100% on anything that we take... what works for 95% of people leaves a 5% ratio that may have other effects... there's no SCIENCE or BRO SCIENCE in that whatsoever... that's just the difference in body types... that's why things are never 100% guaranteed because body makeup cannot be pre determined... I have never heard of the problems you are having with sarms, especially ostarine which has had very few instances of any side effects... any side effects that it can bring generally occur when people abuse the dosage and exceed 25mg... IS IT POSSIBLE that 25 may be a bit much for you, or that your body is rejecting it entirely... YES THAT'S POSSIBLE... is it a normal thing, NO ITS NOT... It could be come down to quite a few things... You never mentioned where you bought it, what your history of certain conditions are, allergies, etc... You were never given an eval to determine any of these things... So before you go around making asshole condescending comments, take a look at yourself and what you are writing first... I know that I help so many people daily, ON MY FREE TIME, and continually GIVE to this community... I and many others are not getting paid for this... I have a masters degree for a reason, because I put in my time into studies, etc... This is WHAT I DO FOR A LIVING... as much as I TRY TO FREELY GIVE, I don't have time to GIVE SCIENTIFIC answers on a daily basis to every question... I try to sum it up the best I can on each question... Do you realize I get nearly 75 pm's A DAY and I ANSWER EVERY LAST ONE OF THEM, not to mention all the threads I go through to help... WHO DOES THAT ON ALL THEIR FREE TIME? NOT MANY... Instead of being unappreciative and coming acorss as a jerk, maybe next time you can be appreciative of FREE HELP and just ask for a bit more explanation if your not satisfied with an answer...

I don't know why you think this thread is a personal attack? As a scientist, I am interested in the rare responses which is why I started this thread. Did I ever say that SARM's are bad or that most people have issues? However, just because I haven't read something in PubMed doesn't mean it can't happen. Perhaps more importantly to me, why do you assume I don't do "this" for a living also? If an individual came to me with a strange response to a prescribed medication, what would you think my liability would be if I sent them away and something happened to them? I'm just looking for a free exchange of information based on a larger sample size. If that is unacceptable to the forum, so be it.

 

[Nelson Montana]

I'm in the middle. I think SARM has its place but it's not the holy grail of androgens. I think it's foolish to assume that ANY drug does not have side effects , because they all do. And SARMS is new and relatively untested under stern conditions. As it stands, the only thing I think everyone should understand is that SARMS will certainly suppress -- not as quickly as steroids , but they are not suppression free. So keep that in mind.

 

[stevesmi]

these are RESEARCH CHEMICALS and are NOT for human consumption.

on this site we do not endorse using them on humans. use them on your rats.

the rules are in the sticky

 

[Aesthetical]

Head to toe itchy body rash in week 3 of a 8 week 50mg s-4, 25mg osta. I'm assuming its because of the osta though.