I had the 50ml bottle and it made me sore as hell by itself but when I took it with Deca I didn't have any problems. My first run of it was 250mg for 10 weeks and had pretty good gains but my best gains came after I took 5 weeks off and ran 750 mg. My last few weeks my ass cheek swole up pretty bad and started peeling around the injection site. I used 23 g 1.5 in pin.