moose11 said:nolva, femera,arimidex,?? a combo of any/all? anyone have something thats worked for them to bring ur puffy nips down...i want to try something before i go to surgery. Ive got them naturally and from AAS. Im off now atleast until after surgery if it gets to that.
jayboy said:i had a huge gyno knot from deca and nolva did not do anything, as i did not expect it to since it was progestrone related, i took letro and it was gone in three weeks from what i know letro is the only one that will help with natural gyno, b6 @800mg ed will help to with aas related gyno problems
jrlex said:What is letro?
yes that is correct, but were not talking about surgerychase152 said:I thought you could only get rid of natural through surgery. Let me know if I'm wrong...
bruce410 said:nolva can help gyno that is already there, but i think nolva is the way to go for puffy nips
got muscle said:its the same thing as femara
Letrozole is the chemical name of Novartis’ selective third generationAromatase Inhibitor (AI). This drug was developed to fight breast cancer by inhibiting the aromatization. It is usually used as a part of an aggressive treatment in post-menopausal women, to fight and reverse the spread of breast cancer after other treatments (such as Tamoxifen therapy) has failed. It’s probably the most efficient product on the market for this purpose currently (5) It is very similar in structure and action to it’s predecessor Arimidex.
Letrozole also does quite a few things which would be of interest to both bodybuilders and athletes. Firstly, it has been shown to reduce estrogen levels by 98% or greater(1). In at least one documented incidence, Letrozole reduced estrogen in the test subject to undetectable levels, and increased LH, FSH and SHBG (4). Clearly this is all of interest to bodybuilders, as less estrogen in the body means less chance of certain side effects such as water-retention, Gynocomastia, and acne. This makes Letrozole an appropriate choice for even the heaviest bulking or cutting cycles including harsh androgens. Also, if you are a competitive bodybuilder, Letrozole is a must have product for contest prep; no other Ancillary compound will produce a dry and tight look like Letro will.
An effective dose of Letrozole is .25-.5mg/day (I use .25mgs/day), but be forewarned, if you go over that amount, it can kill your sex drive. Also worth noting is that there's a rebound effect on your estrogen when you come off Letrozol. Maximum inhibition of the aromatase enzyme has been found to happen at doses as low as 100mcg! (2)
Letrozole's effects on serum lipids (cholesterol, both HDL and LDL) are, in the words of one researcher: "inconsistent. " Clearly, however, you’ll eventually suffer an impaired lipid profile and immune system if you keep your estrogen levels too low for too long. Your sex drive will also probably suffer from extraordinarily low levels of estrogen present.
As previously mentioned, Letrozole can be used to raise LH and FSH (which are hormones which signal your testes to produce more testosterone). It also, of course, will raise your testosterone levels (6) via this mechanism. Again, this is of interest to athletes and bodybuilders for obvious reasons. Letrozole, of course, can be used for post-cycle-therapy (PCT) to raise test levels, but for various reasons, Tamoxifen may be a better choice. Still, I have successfully used Letrozole for this purpose.
How good is this compared with Aromasin and Arimidex, it’s too other main rivals? Well, In non-cellular systems, letrozole is 2-5 times more potent than anastrozole and exemestane in its inhibition of the aromatase enzyme and activity, and in cellular systems it is 10-20x more potent! It also lasts quite a long time in your body,but takes awhile to get going… Letrozole has a whopping 2-4 day (!) ½ life, and you need to take Letrozole for 60 days to get a steady blood plasma level (8).
Those are impressive numbers, but here’s one of the most interesting things about Letrozole:
It may reduce/eliminate/reverse existing gynocomastia!
In a study conducted on mice (*no, I know it’s not perfect), gyno-like-changes in the mammary gland were totally destroyed ! Here’s a direct quote from that study:
“Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated [destroyed] with very low concentrations of the aromatase inhibitor, letrozole.”(7)
In addition, I’ve used Letro to get rid of my own gyno, as has a friend of mine, and we both used it at a dose of 2.5mgs/day, tapering down to .25mgs/day, and then finally off….the gyno never returned in both our cases.
I’d say that this stuff is pretty great, considering its availability and cost (when you consider the fact that .25mgs/day is more than enough protection from estrogen-related sides on most cycles), not to mention it’s overall utility for a variety of functions (destroying gyno, preventing estrogenic sides, and for PCT).
got this from another board
scriptfactory said:Nolva alone works wonders. Many members on this board, including me, have tried it and it worked well. I ran:
60mg ED for about 1 month (until the puffage was down)
20mg ED for 4 months (some people only run 10mg ED)
As long as I remained lean I didn't see any sign of puffy nips but I gained a lot of weight during the holidays last year and it came back a bit. I'm currently running 20mg ED and I have no problems. I'm thinking of running it for 1 straight year to kill it permanently.
I would try Nolva before going for surgery. It can't hurt to try.
chase152 said:I thought you could only get rid of natural through surgery. Let me know if I'm wrong...
ceo my nips are tender but no lumps the nolva has gotten rid of them. however the tenderness still there. should i get some letro as well or will the nolva be enoughceo said:I'm letting you know, you're wrong.
moose11 said:nolva, femera,arimidex,?? a combo of any/all? anyone have something thats worked for them to bring ur puffy nips down...i want to try something before i go to surgery. Ive got them naturally and from AAS. Im off now atleast until after surgery if it gets to that.
got muscle said:its the same thing as femara
Thanks bra!
KOArtist said:From the sounds of that study, Femara is DAMN GOOD for pct too (increased LH, FSH and SHBG?!)
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