22g is no harpoon. I use them religiously. I never have injection pain and usually the needle is in b4 I ever notice. I also have a friend that comkplains about the shot. I laugh at him. I have used an 18g b4 only cause it was all I had at the time and I expected it to hurt but no pain. Also most people just run the needle right in, They dont think about hitting nerves or veins, I do not do this. I shoot in either buttock or shoulder I first find my nerve run my finger down it so I know to stay clear of that area. I then put the point of the needle where I plan to inject, then I apply slow even pressure to guide the needle in. If you go slow enough you can actually feel if you hit a vein so you know if you need to move or adjust the poke. I do not even check for blood anymore cause I 100% know when I hit a vein. Every now and then I will catch one but hitting a vein isnt even that painfull but hit a nerve and you will sure know it. I started cycling off and on around 7 years ago and always use a 22g. That is what I am using today. The shot is the easiest part of being on juice if it's not then your doing something wrong.