I've taken Paxil, Prozac, Effexor, Zoloft, Buspar, Doxepin, Clonazepam. The one that really helps me is the clonazepam (spelling?) It kicks in quickly and helps me sleep...that's mainly what I needed anti-anx/dep meds for originally. It's hard to get the right "one" at the "right" dose. It is hard to get off them, but I agree that if you have the problem DO NOT ignore it and try to do it cold turkey on your own. Tried it, didn't work for me. I guess it depends on the individual. Taking gear has not affected me anx/dep. wise at all, which i was worried about. My libido was affected by several of those listed above...but I seem to be doing ok now with the stuff im taking.