Nicotine is definitely unique from other stimulants, when you take it you definitely feel it working within 5-10 min. Be sure to go slow as in 2mg per day or else you'll start sweating profusely, and feel like someone knocked the wind out of you... then work up when you can tolerate a bit more, but don't go over 21mg. Also, i find it amusing that when an EF supplement is mentioned, a whole platoon replies to the thread.