6-oxo and novedex work and work well:
Willoughby DS, Wilborn C, Taylor L, Campbell W.
Department of Health, Human Performance, and Recreation, Baylor University, Waco, TX 76798-7313, USA.
This study examined the effects of an aromatase-inhibiting nutritional supplement on serum steroid hormones, body composition, and clinical safety markers. Sixteen eugonadal young men ingested either Novedex XT or a placebo daily for 8 wk, followed by a 3-wk washout period. Body composition was assessed and blood and urine samples obtained at weeks 0, 4, 8, and 11. Data were analyzed by 2-way repeated-measures ANOVA. Novedex XT resulted in average increases of 283%, 625%, 566%, and 438% for total testosterone (P=0.001), free testosterone (P=0.001), dihydrotestosterone (P=0.001), and the testosterone:estrogen ratio (P=0.001), respectively, whereas fat mass decreased 3.5% (P=0.026) during supplementation. No significant differences were observed in blood and urinary clinical safety markers or for any of the other serum hormones (P>0.05). This study indicates that Novedex XT significantly increases serum androgen levels and decreases fat mass.
PMID: 17460335 [PubMed - indexed for MEDLINE]
now for 6-oxo:
A study was recently completed at Baylor University that looked at the physiological responses to 8 week cycles of 6-OXO. In this study, there were two groups – one that consumed 300mg 6-OXO a day and one that consumed 600mg a day. Each group took the 6-OXO for 8 weeks during which blood samples were taken at intervals throughout the cycle and at 3 weeks after the completion of the cycle. The blood was later analyzed for hormone levels and for toxicity indicators.
The full results cannot be released until the study is peer reviewed, however we can give you a sneak peak at the most important aspect of the study – the influence of 6-OXO upon free testosterone levels.
As you can see from the graph, the 600mg a day group experienced a very substantial increase in free testosterone that was sustained throughout the 8 week cycle. The levels peaked around the 3 week mark, where they measured roughly twice that of baseline levels.
Of particular interest is the fact that after the 3 week washout period, the levels of testosterone for both the 300mg and 600mg groups were pretty much exactly the same as they were at the start of the cycle. This indicates that there are no negative rebound effects upon testosterone levels after cessation of 6-OXO cycles.
It is also important to note that a complete blood panel showed no significant changes in toxicity parameters throughout the course of the cycles.
not bad for otc...