Please Scroll Down to See Forums Below due to illness I am currently taking the drug azatioprine 200mg a day, to controll colitus, while on this drug I need a blood test every three months( to check for any probs is all my doc said). I am looking for any info or comments on juicing while on this medicaton and any complications which this may cause, I have previously done two cycles while on anti inflamitary mesalasine with no problem, but do not know much about azathioprine and how it works, all I know is that it suppresses my immune system, but I am all geared up for my third cycle and have noone who can advise me??? Thanks for any help, and thanks for reactivating my account to whoever this may concern as I do use this site almost every week.. cheers turtle
one for a doc (boring to everyone else)
- Thread starter turtle3
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juicin'since17
New member
isnt colitus where you got the runs all the time? if so id stick with injectables-
geoffgarst
New member
Are you on Azathioprine for a Kidney Transplant or RA (Rheumatoid Arthritis)? I assume RA since you were taking the anti-inflamm drug before.
Azathioprine can cause an increase in cancer risk when used long-term. This particular risk increases in patients with a prior history of treatment with other powerful immunosuppressants, such as Cytoxan, Leukeran, and Alkeran. It also increases the risk of serious infections. Azathioprine can impair fertility by reducing sperm counts in males. Because azathioprine's toxicity increases when taken with the gout medication allopurinol (Zyloprim), its dose is reduced with simultaneous use. Severely low white blood counts can occur when taken with other drugs that can affect the bone marrow or with ACE-inhibitor class drugs used to treat elevated blood pressure, such as Accupril and Vasotec.
The most common serious side effects of azathioprine involve the blood elements and gastrointestinal system. Azathioprine can cause serious lowering of the white blood cell count, resulting in an increased risk of infections. This can reverse when the dose is reduced or temporarily discontinued. Azathioprine can cause nausea, vomiting, and loss of appetite, which can resolve when the dose is reduced or divided through the day. Azathioprine can also cause liver toxicity (in less than 1% of rheumatoid arthritis patients). All patients taking azathioprine require regular blood testing for blood counts and liver function tests for monitoring. Other side effects encountered less frequently include fatigue, hair loss, joint pains, and diarrhea.
I certainly would not be using any AAS while taking Azatioprine. I feel the combination of the two could cause a severe imbalance in your system.
Azathioprine can cause an increase in cancer risk when used long-term. This particular risk increases in patients with a prior history of treatment with other powerful immunosuppressants, such as Cytoxan, Leukeran, and Alkeran. It also increases the risk of serious infections. Azathioprine can impair fertility by reducing sperm counts in males. Because azathioprine's toxicity increases when taken with the gout medication allopurinol (Zyloprim), its dose is reduced with simultaneous use. Severely low white blood counts can occur when taken with other drugs that can affect the bone marrow or with ACE-inhibitor class drugs used to treat elevated blood pressure, such as Accupril and Vasotec.
The most common serious side effects of azathioprine involve the blood elements and gastrointestinal system. Azathioprine can cause serious lowering of the white blood cell count, resulting in an increased risk of infections. This can reverse when the dose is reduced or temporarily discontinued. Azathioprine can cause nausea, vomiting, and loss of appetite, which can resolve when the dose is reduced or divided through the day. Azathioprine can also cause liver toxicity (in less than 1% of rheumatoid arthritis patients). All patients taking azathioprine require regular blood testing for blood counts and liver function tests for monitoring. Other side effects encountered less frequently include fatigue, hair loss, joint pains, and diarrhea.
I certainly would not be using any AAS while taking Azatioprine. I feel the combination of the two could cause a severe imbalance in your system.
geoffgarst
New member
To elaborate to those who do not know about Azathioprine:
This is how it works:
Azathioprine disrupts the synthesis of DNA and RNA. This means that it disrupts cell division and that tissues with relatively rapid cell division are especially prone to its effects. In the treatment of immune mediated diseases, it is the stimulated lymphocytes that are inappropriately attacking the body that become the prime target of azathioprine.
Because Azathioprine can disrupt rapid cell division, its use also has application in treating cancers.
Because Azathioprine is a DNA poison it has the potential to cause mutation.
One of the main issues with azathioprine is a problem with the bone marrow suppression. Cells of the bone marrow are rapidly dividing and thus at risk for suppression from azathioprine. For this reason, at least in early stages of use, Complete Blood Counts (“CBC’s”) are monitored frequently (typically every 2 weeks for the first couple of months).
Some patients can develop liver toxicity to the drug, for this reason, AAS can also play ravoc on your hepatic system (liver).
PS karma is always welcome here.
This is how it works:
Azathioprine disrupts the synthesis of DNA and RNA. This means that it disrupts cell division and that tissues with relatively rapid cell division are especially prone to its effects. In the treatment of immune mediated diseases, it is the stimulated lymphocytes that are inappropriately attacking the body that become the prime target of azathioprine.
Because Azathioprine can disrupt rapid cell division, its use also has application in treating cancers.
Because Azathioprine is a DNA poison it has the potential to cause mutation.
One of the main issues with azathioprine is a problem with the bone marrow suppression. Cells of the bone marrow are rapidly dividing and thus at risk for suppression from azathioprine. For this reason, at least in early stages of use, Complete Blood Counts (“CBC’s”) are monitored frequently (typically every 2 weeks for the first couple of months).
Some patients can develop liver toxicity to the drug, for this reason, AAS can also play ravoc on your hepatic system (liver).
PS karma is always welcome here.
geoffgarst
New member
Hey...I think I agree with DrJMW post!
Silent Method
New member
Good stuff geoffgarst, I fully agree with your recomendation as well. Karma for you.
We use AAS because of it's ability to accelerate physiological adaptation. Azathioprine has potential effects that we do not want accelerated, nor do we want our physiology to adapt to. Regardless of what is on the books as to any degree to which AAS and azathioprine may interact, given the unfathomable dynamics of physiology, these are two drugs that I would not mix.
We use AAS because of it's ability to accelerate physiological adaptation. Azathioprine has potential effects that we do not want accelerated, nor do we want our physiology to adapt to. Regardless of what is on the books as to any degree to which AAS and azathioprine may interact, given the unfathomable dynamics of physiology, these are two drugs that I would not mix.
geoffgarst
New member
Thanks for all the great compliments. Just post or PM me if you have any questions regarding your health. I will always try my best and will tell you if it is beyond my scope.
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