I think it established research that steroid use increases the size of the left ventricle. However, it is speculation what affect this has on lifespan, etc. Kinda scary to think about though. I have heart disease in my family.
Also, his remark about looking shitty 10-20 years later is bullshit. If you juice like crazy for 10-20 years then stop, of course you will look like shit. You will lose much of your muscle mass but still have all that stretched skin. Now, if 20 years later you go on HRT and keep training, then you are going to look better than most people your age.