In the end...it really won't matter much. Your genetics will give you what your genetics will give you. I haven't been over 5 reps in the squat in a long long time and my legs are about 30". I also have some veins and cross-striations in them. I've always had the cross-striation and had lean legs.
I hardly ever go over 5 reps on any exercise (except arms) and I tipped the scale this morning at 293 lbs.
People see pictures of powerlifters and say that they are not big. Those people have never seen REAL top of the line powerlifters before. 33" thighs, 22" arms, huge freaking chests, traps that their shirts cant fit, erectors that look like a vertical set of arms. And don't get me started on top strongmen.
All in all...big people are going to be big if they eat and train hard. Till you have eaten and trained big and hard for many many years and laid a HUGE foundation...forget about if you should be doing 5's or 10's. Just get in the gym and pick a set of reps and train freaking hard.