Re: Mr.X,Macro..........Do I need anti-e?
drwoody said:
I am about to start a mild summer cutting cycle.
400mgs Primo a week for 10 weeks
50mgs Winny ed for 6 weeks.
I will throw in 200mgs Deca a week for the 10 weeks just a lube for my shoulders.
Do I need to run an anti -e during my cycle seeing as the deca dosage is very low?
I am prone to gyno and already have a very mild case of it naturally.
I have armidex,clomid and nolvadex on hand.
I have had a few differnt opions on this already so I am a bit confused,any help is greatly appreciated.
First, not to flame too much cause you are new. Asking mods outright is time consuming for them and insulting to other vets on this board who have a lot to offer.
Second, there is no reason to run an anti-e "just because" on that combo. The chance of gyno is quite low to begin with for the average user, and TMX (tamoxifen), anastrazole (arimidex, or other aromatase inhibitors) don't seem to have an impact on those who are prone to nandrolone mediated deca. Nandrolone has a very low aromatization rate to Estrogen (E2) as well, some say absent.
Here are some novel thoughts on what might help deca gyno (And I think they have been proposed before many times but the mechanism not fully explained).
Requip or Dostinex or even Bromocriptine are DA (dopamine) agonists, Dostinex is more D2 specific, and decrease prolactin secretion, which can be enhanced by progesterone (and Nandrolone being potentially progestin-like) can promote gyno possibly through this way or directly through progestin-activity.
The only way I know of now to block progestin activity is RU-486 (mifepristone), but unfortunately when these are taken for prolonged periods of time at dosage necessary, it also has an anti-glucocorticoid effect (which is stronger than its anti progestin effect). You may be thinking, shit, less cortisol action, bonus!
Wrong, NOT bonus. Studies that have seen these were pulled because patients taking this (ass a possible anti-fertility agent) went into an addisonian-like crisis (hypotension, mental status changes, salt wasting, electrolyte imbalances, arrhythmias). I wouldn't try it.
NFG