You'll want to check the drug interactions for the drugs that you are taking and see if they're ok to take together. Most of the time, except for a few specific antibiotics, you'll be fine with taking any type of steroid along with them. I have been running Doxycycline and/or Minocycline now since April while on and off of gear and have had no problems. Alot of the problem is not with the gear not working but with your digestive system being all out of whack because not just the bad bacteria is eliminated but the healthy bacteria also. Make sure you eat a lot of light yogurt and take supplemental acidophilus while on antibiotics!