Lipostabil transdermal?

[x_muscle]

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[MrMakaveli]

Interesting. Never heard of this product before. I have no doubt the idea has been tried but I think the finding a delivery platform suitable to deliver it to fat cells and not have it absorbed into the blood stream quickly is going to be the hard part. Wonder what kind of delivery solution they used?

I think I read PC is actually used in PLO-gel a transdermal carrier (going to assume this is what Fonz was referring too).

Btw, Karma, good find.

 

[x_muscle]

Its very new, so I don't think there will be any comparative feedback out anywhere though.
Ingredients: Isopropyl alcohol, benzyl alcohol, octyl salicylate, triglyceride complex, water, d-limonene, carbomer.

 

[jacshelb]

This may be a dumb question, but, what's wrong with DMSO as a carrier? Too fast?

Also, is there a good (read as: cheap cheap cheap!) source for PC powder already around? Isn't PC found in lectithin in varying amounts of 20-90%? Or am I way off on this?

What about mixing in some acetyl-L carnatine powder just in case? Or, what about finding a substance that will slow down the uptake once through the dermal layers? Hmmmm.... Fun things to think about. I like this thread. Let's keep it going.


Jacob

 

[kbrkbr]

Interesting thread. I've been looking into lipostabil myself. Was going to order from zipmed, but they don't guarantee delivery to CA and WU wanted to charge me $33 just for transferring funds.

I've found a lab that sells 94% phosphatidylcholine, 25 grams for around $52, but the site says it must be shipped frozen, which leads me to believe it's not in a stable form.

Obviously you couldn't inject this raw form: I understand that most lipostabil products are only around 20-25% phosphatidylcholine. Animal actually sells a kit to convert raw phosphatidylcholine into lipostabil, but charges $50 to convert 6 g. which seems a bit high to me.

Still looking for other alternatives.

 

[MrMakaveli]

Slowing absporption is somthing to be looked into, I found a ton of stuff on PC actually behing used as a carrier for other things itself so I have to take a look and see what I can draw from that. We need more chemists on this thread my knowledge is severely lacking haha.

 

[x_muscle]

they changed the description of the product, since yesterday. it says phospholipid instead phosphatidylcholine. phospholipids is a large group of molecuales that include phosphatidylcholine.

 

[x_muscle]

also i found this place. they pure phosphatidylcholine powder

http://www.liverfriend.com/index.php?cPath=2_35

 

[drveejay11]

We need Andy13 on this one!!!

 

[sigmund]

Suggestion as to relatively inexpensive lipostabil transdermal:

Using a delivery system similar to Finasol-

- 80ml Water
- 50ml Isopropyl Myristate
- 110ml 99% Isopropyl Alcohol

Dissolve Phosphatidylcholine powder in the above solution (not sure on amount, maybe 100 - 150g?).

Add to spray bottle, apply frequently during the day.

Main problem is still the speedy absorption but frequent application throughout the day could remedy this.

Feedback / opinions welcome

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For ref:

99% Isopropyl Alcohol
http://www.electronics-plus.com/Mer...lus&Product_Code=824-350ML&Category_Code=CLCH
$4.95

Isopropyl Myristate
http://www.lemelange.com/oil_liquid_cream_wax_g_-_p.htm
$10.50 480ml (16 oz)

Phosphatidylcholine (thanks to x_muscle for locating this)
http://www.liverfriend.com/index.php?cPath=2_35
$30.00 (500g)
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