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Letrozole Vs. Nolvadex

Pros / Cons of each ???
Which one do people prefer ?
Why is one superior to the other??
Everyone share...


Vets and Mods please get some good information on this thread...
 
it depends on what you need them for....i have never used nolva..but letrozole did great for completely removing all signs of gyno in less than 2 weeks.
 
Letrozole seems to be very similar to Arimidex in the sense that it works by blocking the enzyme aromatase, subsequently blocking the production of estrogen.

It also has the same drawbacks as arimidex being (from stroidology.com ):

There are some concerns with using an aromatase inhibitor such as this during prolonged steroid treatment however. While it will effectively reduce estrogenic side effects, it will also block the beneficial properties of estrogen from becoming apparent (namely its effect on cholesterol values). Studies have clearly shown that when an aromatase inhibitor is used in conjunction with a steroid such as testosterone, suppression of HDL (good) cholesterol becomes much more pronounced. Apparently estrogen plays a role in minimizing the negative impact of steroid use. Since the estrogen receptor antagonist Nolvadex does not display an anti-estrogenic effect on cholesterol values, it is the preferred from of estrogen maintenance for those concerned with cardiovascular health.
 
slash747 said:
Letrozole seems to be very similar to Arimidex in the sense that it works by blocking the enzyme aromatase, subsequently blocking the production of estrogen.

It also has the same drawbacks as arimidex being (from stroidology.com ):

There are some concerns with using an aromatase inhibitor such as this during prolonged steroid treatment however. While it will effectively reduce estrogenic side effects, it will also block the beneficial properties of estrogen from becoming apparent (namely its effect on cholesterol values). Studies have clearly shown that when an aromatase inhibitor is used in conjunction with a steroid such as testosterone, suppression of HDL (good) cholesterol becomes much more pronounced. Apparently estrogen plays a role in minimizing the negative impact of steroid use. Since the estrogen receptor antagonist Nolvadex does not display an anti-estrogenic effect on cholesterol values, it is the preferred from of estrogen maintenance for those concerned with cardiovascular health.


thanks slash747, that is some good info and insight ...
 
The Terminator said:
Letrozole is far superior for controlling estrogen BEFORE it gets out of hand...
Once circulating estrogen gets to a problematic level though Nolva is necessary...

From the few sources I have read , it seems like having a little estrogen in youre body actually helps with youre cholesterol levels. With armimidex/femara, dont you pretty much eliminate the conversion to estrogen in youre body?

Would it maybee helped if you took the two in conjunction with each other? Take the letrozole at a really low dose to keep estrogen levels in check and take the nolva to be on the safe side.

Im not an expert on the subject but it seems unless youre getting blood tests on the regular while on a letrozole, it has the potential to be problematic.
 
2 totally different compounds. Now if you were comparing ana to letro...
 
i got no science to prove this, but i swear letro works better than ana....

i do not hold one tad of water with letro, it reduced bloat for me a lot more then ana.

can't explain the why part though.
 
Studies also show that nolvadex reduces the concentration of letrozole by up to 35-40%! This has been making me think lately that for those are prone to gyne it might be better to run a-dex/nolva intead of using femara/nolva, although femara is supposed to be a more potent AI!
 
Letro will kill your sex drive and Nolva will not. Taking test with no sex drive is crazy. Usually test makes you one horny mother. But not with letro. I learned that lesson the hard way. You need circulating estrogen for sex drive, so just use Nolva to prevent estro from binding to the receptors in breast tissue.
 
bbkingpinn said:
Letro will kill your sex drive and Nolva will not. Taking test with no sex drive is crazy. Usually test makes you one horny mother. But not with letro. I learned that lesson the hard way. You need circulating estrogen for sex drive, so just use Nolva to prevent estro from binding to the receptors in breast tissue.

Nolva will help with gyno, but not much in the way of water retention! I think it is important to start with very small doses of AI's such as arimdex/letro and really monitor your bodies response until you get the dosages tweeked!
Use the AI's during cycle and if gyno symptoms occur better get on the nolvadex!
 
Nolva will reduce IGF levels whereas Letro doesn't, but letro is worse for your Cholesterol/BP. Having some estrogen is not a bad thing, as long as you don't get gyno, so I would opt for Nolva usually.
 
If you want to control water retention/bloat you need an aromatase inhibitor!

If all you are worried about is gyno then you can just just go with some nolvadex!

I always have both!
 
letro is stronger than arimidex...To strong if ya ask me

Aromasin is superior to both{does not fuck with your lipids}

Nolvadex is great and I try to always have some on hand...
 
^agreed, however if you are trying to avoid bloat the most effective at the task is letro. If it weren't for the cost issue I would only use aromasin.
 
jubei said:
^agreed, however if you are trying to avoid bloat the most effective at the task is letro. If it weren't for the cost issue I would only use aromasin.
true...letro is stronger as far as cotrolling bloat...I love letro but it kills my sex drive...I'm using upjohn aromasin now...and it's not to cheap.
 
For those using aromasin, what is your dosage amount and schedule? Do you run it ed or eod?
 
Fat Sumo- I will be running a 20-25mgs dbol for the first 4 weeks of a 12 week Test/Eq Cycle. Test will be ran at 400mgs/wk, Eq @ 500mg/wk. The last 6 weeks I will add Winny @ 50mgs/day. Thanks for any suggestions. BTW, I am currently 5'9" and 188 lbs @ 10%BF.
 
muscleup said:
true...letro is stronger as far as cotrolling bloat...I love letro but it kills my sex drive...I'm using upjohn aromasin now...and it's not to cheap.

letro murders my sex drive. ive never had anything do it like letro.

ive used hefty doses of tren/test, and post-cycle libido crash wasn't bad at all. letro is in a whole nother league.

it works soooo damn good though. its a love/hate thing.
 
Good I need something to curb my sex drive when training. The combo of test prop/dbol/tren and letro has me with virtually no side effects and clear skin. The no sex drive thing is fine, cause my dick gets hard when it needs to anyways. Test boners 24/7 gets a bit old after a while. Who am I kidding, no I doesn't.
 
jubei said:
Good I need something to curb my sex drive when training. The combo of test prop/dbol/tren and letro has me with virtually no side effects and clear skin. The no sex drive thing is fine, cause my dick gets hard when it needs to anyways. Test boners 24/7 gets a bit old after a while. Who am I kidding, no I doesn't.
DAMN YOU...LMAO
 
Actually I broke out pretty bad my last 2 cycles. Both were test only (sustanon). Even on this one I started out with prop/winstrol until my joints couldn't take it and switched to dbol. Funny thing is, when I started the tren my skin cleared up and my nuts got a little bigger. This is some fucked up shit.
 
These two drugs are kind of hard to compare. Nolva dose little for water retention. I have found the two best uses for nolva to be gyno prevention and post cycle recovery. If I am worried about water retention then I use something to suppress aromatise such as adex. Even with nolva you still have test converting to estrogen via the aromatise enzyme. Two totally different uses IMO.
 
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