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Issues with testosterone

chesty

Bodybuilding Competitor
Elite Moderator
Since reading the threads on just how bad Novaldex can be, I thought I would look up some side effects of testosterone use.

Testosterone Side Effects | Drugs.com

Testosterone Side Effects

Brand Names: AndroGel, Androderm, Androgel, Delatestryl, Depo-Testosterone, Striant, Testim, Testosterone Enanthate

Please note - some side effects for Testosterone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at MedWatch: The FDA Safety Information and Adverse Event Reporting Program or 1-800-FDA-1088 (1-800-332-1088).
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Side Effects of Testosterone - for the Consumer
Testosterone

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Testosterone:

Acne; bitter or strange taste in mouth; change in sex drive; fatigue; gum or mouth irritation; gum pain; gum tenderness or swelling; hair loss; headache.

Seek medical attention right away if any of these SEVERE side effects occur when using Testosterone:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast growth or pain; change in the size or shape of the testicles; dark urine or light-colored bowel movements; depression or mood changes; dizziness; gingivitis; interrupted breathing while sleeping; loss of appetite; nausea; painful or prolonged erection; stomach pain; swelling of the ankles or legs; urination problems; weight gain; yellowing of the skin or eyes.

Testosterone Cypionate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Testosterone Cypionate:

Acne; bitter or strange taste in mouth; change in sex drive; fatigue; gum or mouth irritation; gum pain; gum tenderness or swelling; hair loss; headache.

Seek medical attention right away if any of these SEVERE side effects occur when using Testosterone Cypionate:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast growth or pain; change in the size or shape of the testicles; dark urine or light-colored bowel movements; depression or mood changes; dizziness; gingivitis; interrupted breathing while sleeping; loss of appetite; nausea; painful or prolonged erection; stomach pain; swelling of the ankles or legs; urination problems; weight gain; yellowing of the skin or eyes.

Testosterone Enanthate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Testosterone Enanthate:

Acne; bitter or strange taste in mouth; change in sex drive; fatigue; gum or mouth irritation; gum pain; gum tenderness or swelling; hair loss; headache.

Seek medical attention right away if any of these SEVERE side effects occur when using Testosterone Enanthate:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast growth or pain; change in the size or shape of the testicles; changes in menstrual periods; coughing fit; dark urine or light-colored bowel movements; depression or mood changes; dizziness; facial hair growth; gingivitis; interrupted breathing while sleeping; loss of appetite; nausea; painful or prolonged erection; shortness of breath; stomach pain; swelling of the ankles or legs; urination problems; voice changes or hoarseness; weight gain; yellowing of the skin or eyes.

Testosterone Gel

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Testosterone Gel:

Acne; breast tenderness or enlargement; change in sex drive; headache; skin irritation at the application site.

Seek medical attention right away if any of these SEVERE side effects occur when using Testosterone Gel:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); calf pain, swelling, or redness; change in the size or shape of the testicles; dark urine; excessive daytime sleepiness; frequent, prolonged, or painful erections; interrupted breathing while sleeping; loss of appetite; memory problems; mood or mental changes (eg, anxiety, depression, hostility, suicidal thoughts); nausea; new or worsening trouble urinating (eg, frequent urination, inability to urinate, weak urine stream); pale stools; severe headache; skin discoloration; stomach pain; swelling of the ankles or legs; trouble sleeping or other sleep changes; unexplained or unusual weight gain; unusual tiredness or weakness; vomiting; yellowing of the skin or eyes.

Testosterone Patch

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Testosterone Patch:

Acne; bitter or strange taste in mouth; change in sex drive; fatigue; gum or mouth irritation; gum pain; gum tenderness or swelling; hair loss; headache.

Seek medical attention right away if any of these SEVERE side effects occur when using Testosterone Patch:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast growth or pain; change in the size or shape of the testicles; dark urine or light-colored bowel movements; depression or mood changes; dizziness; gingivitis; interrupted breathing while sleeping; loss of appetite; nausea; painful or prolonged erection; stomach pain; swelling of the ankles or legs; urination problems; weight gain; yellowing of the skin or eyes.

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Testosterone Side Effects - for the Professional
Testosterone

The following adverse reactions in the male have occurred with some androgens:
Endocrine and Urogenital

Gynecomastia and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages.
Skin and Appendages

Hirsutism, male pattern of baldness, seborrhea, and acne.
Fluid and Electrolyte Disturbances

Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
Gastrointestinal

Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis.
Hematologic

Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
Nervous System

Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
Allergic

Hypersensitivity, including skin manifestations and anaphylactoid reactions.
Miscellaneous

Inflammation and pain at the site of intramuscular injection.
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Side Effects by Body System
Cardiovascular

Cardiovascular side effects have included hypertension, and edema with and without congestive heart failure.
Endocrine

Endocrine side effects have included gynecomastia as a frequent and sometimes persistent side effect. Cautious use is recommended in patients with existing gynecomastia.

During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). Large doses of exogenous androgens may suppress spermatogenesis through inhibition of pituitary follicle stimulating hormone (FSH).

Androgens may decrease levels of thyroxin binding globulin resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged and there is no clinical evidence of thyroid dysfunction.

Changes in insulin sensitivity or glycemic control may occur in patients treated with androgens. In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.

Virilization of children has been reported due to secondary exposure to testosterone. Signs and symptoms have included inappropriate enlargement of the penis or clitoris, premature development of pubic hair, increased erections and libido, aggressive behavior, and advanced bone age. In most cases, these signs and symptoms regressed with removal of the exposure to testosterone. In a few cases, however, enlarged genitalia did not fully return to age-appropriate normal size and bone age remained modestly greater than chronological age.
Renal

Renal side effects have included retention of nitrogen, sodium, potassium, chloride, water and phosphorus, and decreased urinary excretion of calcium.
Hepatic

Hepatic side effects have included life-threatening peliosis hepatitis and hepatic abnormalities including hepatic neoplasms and hepatocellular carcinomas following prolonged therapy with high doses of androgen. Tumor regression did not occur in all cases following medication withdrawal.

Cholestatic hepatitis, jaundice, and abnormal liver function tests have occurred during androgen therapy. Drug-induced jaundice is usually reversible following drug discontinuation.
Genitourinary

Genitourinary side effects following chronic administration and/or large dosages of testosterone have included oligospermia and decreased ejaculatory volume. Elderly male patients have experienced prostatic enlargement resulting in urinary obstruction. Priapism and excessive stimulation has developed. Other urinary side effects have included nocturia, urinary hesitancy, urinary incontinence, urinary retention, urinary urgency, and weak urinary system.

In female patients the use of androgens has resulted in virilization including deepening voice, hirsutism, acne, clitomegaly (not reversible), and menstrual abnormalities. Discontinuation of testosterone at signs of mild virilization may prevent irreversible virilization.
Metabolic

Metabolic side effects have included osteolytic-induced hypercalcemia in immobilized patients or those with metastatic breast disease. Increased cholesterol levels and acute intermittent porphyria have been reported.
Other

Other side effects have included virilization in female patients. Virilization included deepening voice, hirsutism, acne, clitomegaly (not reversible), and menstrual abnormalities.

Female sexual partners of men using topical testosterone (residual on skin) have reported virilization.
Dermatologic

Dermatologic side effects have included hirsutism, acne, male-patterned baldness and seborrhea. Dermal reactions have been the most commonly reported side effects for transdermal testosterone and occur primarily at the site of application. Dermal effects have included 3 types: irritation including mild to moderate erythema (to 6%), induration (3%), itching (12%), and burning (3%); allergic contact dermatitis including pruritus (to 37%), vesicles (6%), and rash (2%); and burn-like blisters (12%).

Discontinuation rates for transdermal testosterone were as follows: due to chronic skin irritation (5%), allergic dermal reactions (4%), and burn-like, usually a single site (0%).

Triamcinolone 1% cream applied sparingly to skin under the reservoir reduced irritation and did not interfere with testosterone absorption. Ointment formulations reduce testosterone absorption.
Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.
Musculoskeletal

Testosterone is involved in termination of linear bone growth by closure of the epiphyseal growth centers. Appropriate monitoring of bone age is recommended during testosterone use in healthy males with delayed puberty.

Musculoskeletal side effects have included myalgia and pain.
Hematologic

Hematologic side effects have included alteration in clotting factors II, V, VII and X and polycythemia due to increased red cell production. Anemia has also been reported.
Hypersensitivity

Hypersensitivity side effects have included rash and anaphylactoid reactions.
Local

Local side effects have included inflammation and pain at injection or dermal application site.
Nervous system

Nervous system side effects have included altered libido (increased/decreased), headache (to 5%), anxiety, depression, generalized paresthesia, or sleep apnea syndrome.
Oncologic

Oncologic side effects have included carcinoma of the prostate, hepatic neoplasms, and hepatocellular carcinomas.
Respiratory

Respiratory side effects have included reports of potentiation of sleep apnea, particularly in obese patients or those with chronic lung disease. There have been rare postmarketing reports of transient reactions involving urge to cough, coughing fits, and respiratory distress immediately after the injection of testosterone enanthate, an oil-based depot preparation.
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More Testosterone resources

* testosterone Buccal Advanced Consumer (Micromedex) - Includes Dosage Information
* Testosterone Professional Patient Advice (Wolters Kluwer)
* Testosterone MedFacts Consumer Leaflet (Wolters Kluwer)
* Testosterone Prescribing Information (FDA)
* AndroGel Detailed Consumer Information (PDR)
* AndroGel Gel MedFacts Consumer Leaflet (Wolters Kluwer)
* AndroGel Prescribing Information (FDA)
* Androderm Prescribing Information (FDA)
* Androderm Detailed Consumer Information (PDR)
* Androderm Advanced Consumer (Micromedex) - Includes Dosage Information
* Androderm Patch MedFacts Consumer Leaflet (Wolters Kluwer)
* Androgel Advanced Consumer (Micromedex) - Includes Dosage Information
* Androgel Consumer Overview
* Delatestryl MedFacts Consumer Leaflet (Wolters Kluwer)
* Delatestryl Prescribing Information (FDA)
* Depo-Testosterone Prescribing Information (FDA)
* Depo-Testosterone MedFacts Consumer Leaflet (Wolters Kluwer)
* Striant Consumer Overview
* Striant Prescribing Information (FDA)
* Striant Detailed Consumer Information (PDR)
* Testim Prescribing Information (FDA)
* Testim Gel MedFacts Consumer Leaflet (Wolters Kluwer)
* Testosterone Cypionate Prescribing Information (FDA)
* Testosterone Enanthate Prescribing Information (FDA)

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgment of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.


Read more: Testosterone Side Effects | Drugs.com


I think we all know if we want to play the game at some point we all will have to pay the ferry man his gold coin.
 
Testosterone is KING.

That said having 10x the norm floating around in your body is not normal lol.

On 500mg a week I get some facial bloat and I have to watch my salt intake. Other than that I feel great. I can tell a difference between 250mg a week and 500. I still have boosted recovery off 250, but on 500 it's like I didn't even workout within 5-10 minutes after almost. Systemic recovery is ultra fast for me on 500 or more.

I also tend to get a little sweating at night on the upper chest and shoulder area off 500 which I assume is the high androgen level. Not particularly bothersome, but it's noticeable. I don't get this on 250-300 a week.

I don't use an ai up to 500. In the future I will bump up to 750 and I'm pretty excited about trying that out and seeing how I respond.

At this point in time I wouldn't go over 500mg a week and perhaps 15-20mg dbol a day. 750 first time or 2 would be by itself.

Oh ya, and I'm hairy on test, but that's ok because I was a hairy bastard to begin with HA!

Test is best.

Go look up side effects of aspirin or ibuprofen. SCARY.
 
Well said all. Everything has side effects, eating, not eating, shitting, pissing, walking, running, stretching, working out, well you get the idea. Using sensibly and thoughtfully is key. And of course EDUCATE YOURSELF!!! Thanks for the post chesty and everyone else:D.
 
Most of testosterones sides are actually pretty rare and only with supraphysiological dosages. Nolvadex has sides in low doses and it has none of the health benefits of Test.

Big difference.
 
Test is the king, but I have never personally known anyone that did not get acne from it. For me the sides are too much, I get huge nasty cysts all over my neck, back and chest that require cortisone injections from a dermatologist. I have also had to run accutane after test cycles. I stopped using test years ago, have only used tren, eq and primo (not stacked) for last couple yrs. I get no acne whatsoever from any of these.
 
I would agree that the sides from test may not be as severe as Nolvadex. The only point I was making is that we are playing in a game that has very little room for error. If one is lucky all he/she gets is some acne. At worst, he/she gets dead. And since we chose to play the game, we must also accept the outcomes dealt us, good or bad.

One thing I would like to know is what percentage of persons who were studied consistently developed a serious side effect of any drug, be it Nolvadex or Test. I think we all should always remind ourselves of the seriousness of the game we play and its consequences. And if there is a drug that should not be used no matter what, then we should heed that warning and not use it, especially if the bad outweighs the good a drug can bring.
 
I would agree that the sides from test may not be as severe as Nolvadex. The only point I was making is that we are playing in a game that has very little room for error. If one is lucky all he/she gets is some acne. At worst, he/she gets dead. And since we chose to play the game, we must also accept the outcomes dealt us, good or bad.

One thing I would like to know is what percentage of persons who were studied consistently developed a serious side effect of any drug, be it Nolvadex or Test. I think we all should always remind ourselves of the seriousness of the game we play and its consequences. And if there is a drug that should not be used no matter what, then we should heed that warning and not use it, especially if the bad outweighs the good a drug can bring.

No one has ever died from a few hundred mgs of test. You'd have to take grams of it non stop for years, and if you do, you deserve what comes to you. Nolva on the other hand CAN kill you, but it would also take some heavy dosing. However, it doesn't take muchnolva to make you feel like shit. I never heard anyone say, "Hey, I went from 200 mgs of test to 300 mgs of test and boy, do I feel lousy."
 
Individual tolerance to high levels of test and preventative measures like n2guard etc can drastically reduce side effects.

I have no doubt I could run a gram of test a week and likely need only a small amount of ai to offset the excess water as I don't even use ai on 500.

Some other guy might need ai on 250mg believe it or not because his body doesn't tolerate the water bloat very well.
 
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